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[HTML][HTML] Virulence Factors of Enteric Pathogenic Escherichia coli: A Review
Escherichia coli are remarkably versatile microorganisms and important members of the
normal intestinal microbiota of humans and animals. This harmless commensal organism …
normal intestinal microbiota of humans and animals. This harmless commensal organism …
Citrobacter rodentium–host–microbiota interactions: immunity, bioenergetics and metabolism
Citrobacter rodentium is an extracellular enteric mouse-specific pathogen used to model
infections with human pathogenic Escherichia coli and inflammatory bowel disease. C …
infections with human pathogenic Escherichia coli and inflammatory bowel disease. C …
Pyroptosis-induced inflammation and tissue damage
Programmed cell deaths are pathways involving cells playing an active role in their own
destruction. Depending on the signaling system of the process, programmed cell death can …
destruction. Depending on the signaling system of the process, programmed cell death can …
Enteropathogenic Escherichia coli—A Summary of the Literature
Diarrheal disease is still a major public health concern, as it is still considered an important
cause of death in children under five years of age. A few decades ago, the detection of …
cause of death in children under five years of age. A few decades ago, the detection of …
[HTML][HTML] Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunity
Transfer of the gut microbiota from wild to laboratory mice alters the host's immune status
and enhances resistance to infectious and metabolic diseases, but understanding of which …
and enhances resistance to infectious and metabolic diseases, but understanding of which …
Type III secreted effectors that target mitochondria
A type III secretion system (T3SS) is used by Gram‐negative bacterial pathogens to secrete
and translocate a battery of proteins, termed effectors, from the bacteria directly into the host …
and translocate a battery of proteins, termed effectors, from the bacteria directly into the host …
Microbiota-derived succinate promotes enterohaemorrhagic Escherichia coli virulence via lysine succinylation
L Li, Y Liu, D Liu, J Wang, M Wang, B **ang, J Qin… - Nature …, 2025 - nature.com
Succinate upregulates enterohaemorrhagic Escherichia coli (EHEC) virulence. Lysine
succinylation, a post-translational modification, regulates cellular function in eukaryotes but …
succinylation, a post-translational modification, regulates cellular function in eukaryotes but …
Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx–dependent pyroptosis in intestinal epithelial cells
Clustering of the enteropathogenic Escherichia coli (EPEC) type III secretion system (T3SS)
effector translocated intimin receptor (Tir) by intimin leads to actin polymerisation and …
effector translocated intimin receptor (Tir) by intimin leads to actin polymerisation and …
Enteropathogenic Escherichia coli stimulates effector-driven rapid caspase-4 activation in human macrophages
Microbial infections can stimulate the assembly of inflammasomes, which activate caspase-
1. The gastrointestinal pathogen enteropathogenic Escherichia coli (EPEC) causes …
1. The gastrointestinal pathogen enteropathogenic Escherichia coli (EPEC) causes …
Prophages and plasmids can display opposite trends in the types of accessory genes they carry
Mobile genetic elements (MGEs), such as phages and plasmids, often possess accessory
genes encoding bacterial functions, facilitating bacterial evolution. Are there rules governing …
genes encoding bacterial functions, facilitating bacterial evolution. Are there rules governing …