A growing body of evidence indicates that, over the course of evolution of the immune
system, arginine has been selected as a node for the regulation of immune responses. An …

Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly
mobilized to sites of inflammation and/or infection. At the affected tissues, neutrophils display …

Amino acid metabolism is a critical regulator of the immune response, and its modulating
becomes a promising approach in various forms of immunotherapy. Insufficient …

Myeloid cells can restrain antitumor immunity by metabolic pathways, such as the
degradation of l-arginine, whose concentrations are regulated by the arginase 1 (ARG1) …

Despite considerable recent progress in defining neutrophil functions and behaviors in
tissue repair, much remains to be determined with regards to its overall role in the tissue …

Neutrophils are the most abundant leukocytes in blood and are considered to be the first line
of defense during inflammation and infections. In addition, neutrophils are also found …

Recent years have seen a renaissance in the research linking inflammation and cancer with
immune cells playing a central role in smouldering inflammation in the tumor …

Research on tumor‐associated neutrophils (TAN) currently surges because of the well‐
documented strong clinical relevance of tumor‐infiltrating neutrophils. This relevance is …

In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various
types of cancer, including head and neck squamous cell carcinoma (HNSCC). In this study …