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Extracellular vesicles and nanoparticles: emerging complexities
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …
because recent discoveries have revealed a much greater complexity and diversity than was …
Extracellular vesicle analysis
A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Extracellular vesicles and exomere nanoparticles are under intense investigation as sources
of clinically relevant cargo. Here we report the discovery of a distinct extracellular …
of clinically relevant cargo. Here we report the discovery of a distinct extracellular …
Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy
Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer
nanoparticles secreted by most cells. EVs are regarded as important mediators of …
nanoparticles secreted by most cells. EVs are regarded as important mediators of …
MIBlood‐EV: Minimal information to enhance the quality and reproducibility of blood extracellular vesicle research
Blood is the most commonly used body fluid for extracellular vesicle (EV) research. The
composition of a blood sample and its derivatives (ie, plasma and serum) are not only donor …
composition of a blood sample and its derivatives (ie, plasma and serum) are not only donor …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids
Extracellular vesicles (EVs) are small membranous vesicles that contain an abundant cargo
of different RNA species with specialized functions and clinical implications. Here, we …
of different RNA species with specialized functions and clinical implications. Here, we …
Therapeutic and diagnostic translation of extracellular vesicles in cardiovascular diseases: roadmap to the clinic
Exosomes are small membrane-bound vesicles of endocytic origin that are actively
secreted. The potential of exosomes as effective communicators of biological signaling in …
secreted. The potential of exosomes as effective communicators of biological signaling in …