Citrus fruits are among the most popularly consumed fruits worldwide, including oranges,
grapefruits, pomelos and lemons. Citrus flavonoids such as hesperidin, naringin and …

The barrier function of skin and the non-optimal physicochemical properties of drugs present
challenges to the skin penetration of many drugs, thus motivating the development of novel …

Cocrystallization by the solvent drop grinding technique has been employed successfully to
generate highly water-soluble cocrystals of a poorly soluble nutraceutical hesperetin with …

Nanocrystals are composed of 100% active and possess an increased aqueous solubility
and dissolution velocity when compared to larger sized materials. Nanocrystals can be used …

A significant majority of the 20 approved nanoformulations consist predominantly of
nanocrystals (NCs). NCs are nanosized drug moieties comprising 100% of the drug with …

Advanced drug delivery technologies, in general, enable drug reformulation and
administration routes, together contributing to life-cycle management and allowing the …

Nanocarriers have been widely studied and applied in the field of cancer treatment.
However, conventional nanocarriers still suffer from complicated preparation processes, low …

Background Bioflavonoids, secondary metabolites of plants, are beneficial in regulating
human physiological mechanisms. Bioflavonoids majorly exist in the dietary intake of fruits …

Colon cancer is a major cause of cancer-related death, with significantly increasing rates of
incidence worldwide. The current study was designed to evaluate the anti-carcinogenic …

Type 2 diabetes mellitus (T2DM) is a major chronic disease that is prevalent worldwide, and
it is characterized by an increase in blood glucose, disturbances in the metabolism, and …