Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

Although coronary thrombus overlying a disrupted atherosclerotic plaque has long been
considered the hallmark and the primary therapeutic target for acute myocardial infarction …

Cardiovascular diseases (CVD), including ischemic heart diseases and cerebrovascular
diseases, are the leading causes of morbidity and mortality worldwide. Atherosclerosis is the …

Reactive oxygen species and reactive nitrogen species are biological molecules that play
important roles in cardiovascular physiology and contribute to disease initiation …

Summary Background Lipoprotein (a)(Lp [a]) is a risk factor for cardiovascular disease and
calcific aortic valve stenosis. No effective therapies to lower plasma Lp (a) concentrations …

Prolonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic
inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma …

This study reviews ancestral differences in the genetics of the LPA gene, risk categories of
elevated lipoprotein (a)[Lp (a)] as defined by guidelines, ancestry-specific Lp (a) risk …

Elevated plasma concentrations of lipoprotein (a)[Lp (a)] have been determined to be a
causal risk factor for coronary heart disease, and may similarly play a role in other …

Abstract Lipoprotein (a)(Lp (a)) is associated with atherothrombosis through several
mechanisms, including putative antifibrinolytic properties. However, genetic association …

Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory
response in mammals. Due to these roles in inflammation, plasminogen has been …