Both normal aging and Alzheimer's disease (AD) are associated with changes in cognition,
grey and white matter volume, white matter integrity, neural activation, functional …

Vascular cognitive impairment (VCI) is the diagnostic term used to describe a
heterogeneous group of sporadic and hereditary diseases of the large and small blood …

Resolving glial contributions to Alzheimer's disease (AD) is necessary because changes in
neuronal function, such as reduced synaptic density, altered electrophysiological properties …

Background Early and accurate diagnosis of Alzheimer's disease (AD) is essential for
disease management and therapeutic choices that can delay disease progression. Machine …

Voxel-based analysis of diffusion MRI data is increasingly popular. However, most white
matter voxels contain contributions from multiple fibre populations (often referred to as …

The distribution of brain aerobic glycolysis (AG) in normal young adults correlates spatially
with amyloid-beta (Aβ) deposition in individuals with symptomatic and preclinical Alzheimer …

Background Diffusion tensor imaging (DTI) is applied in investigation of brain biomarkers for
neurodevelopmental and neurodegenerative disorders. However, the quality of DTI …

There is a long history linking traumatic brain injury (TBI) with the development of dementia.
Despite significant reservations, such as recall bias or concluding causality for TBI, a …

Importance Patients who have experienced intracerebral hemorrhage (ICH) appear to
develop cognitive impairment at high rates, both early after ICH and over the long term …

Purpose To investigate microstructural alterations in white matter in mild cognitive
impairment (MCI) and Alzheimer's disease (AD) using neurite orientation dispersion and …