Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
western world. In the last three decades, fluid dynamics investigations have been an …

Healthcare is under increasing demand pressure as societies age and expectations rise,
multiplied by increasing incidence of chronic diseases and decreasing available funding …

Physics-based models can be applied to describe mechanisms in both health and disease,
which has the potential to accelerate the development of personalized medicine. The aim of …

The Frank-Starling mechanism is a fundamental regulatory property which underlies the
cardiac output adaptation to venous filling. Length-dependent activation is generally …

We aim to clarify our understanding of the process of state-space model input parameter
identification, known, within the clinical context, as model personalisation. To do so, we …

Mathematical models are essential tools to study how the cardiovascular system maintains
homeostasis. The utility of such models is limited by the accuracy of their predictions, which …

In-vivo studies of pulmonary vascular disease and pulmonary hypertension (PH) have
provided key insight into the progression of right ventricular (RV) dysfunction. Additional in …

Pulmonary artery stenosis (PAS) often presents in children with congenital heart disease,
altering blood flow and pressure during critical periods of growth and development …

Purpose Fabrication of a suitable flow model or phantom is critical to the study of biomedical
fluid dynamics using optical flow visualization and measurement methods. The main …

Background and objective Parameters of mathematical models of the cardiovascular system
can be used to monitor cardiovascular state, such as total stressed blood volume status …