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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
W Filipowicz, SN Bhattacharyya… - Nature reviews …, 2008 - nature.com
MicroRNAs constitute a large family of small, approximately 21-nucleotide-long, non-coding
RNAs that have emerged as key post-transcriptional regulators of gene expression in …
RNAs that have emerged as key post-transcriptional regulators of gene expression in …
The gap gene network
J Jaeger - Cellular and Molecular Life Sciences, 2011 - Springer
Gap genes are involved in segment determination during the early development of the fruit
fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize …
fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize …
Screening cell–cell communication in spatial transcriptomics via collective optimal transport
Spatial transcriptomic technologies and spatially annotated single-cell RNA sequencing
datasets provide unprecedented opportunities to dissect cell–cell communication (CCC) …
datasets provide unprecedented opportunities to dissect cell–cell communication (CCC) …
A survey on incomplete multiview clustering
Conventional multiview clustering seeks to partition data into respective groups based on
the assumption that all views are fully observed. However, in practical applications, such as …
the assumption that all views are fully observed. However, in practical applications, such as …
Transcriptional coupling of distant regulatory genes in living embryos
The prevailing view of metazoan gene regulation is that individual genes are independently
regulated by their own dedicated sets of transcriptional enhancers. Past studies have …
regulated by their own dedicated sets of transcriptional enhancers. Past studies have …
Construction of a 3D whole organism spatial atlas by joint modelling of multiple slices with deep neural networks
Spatial transcriptomics (ST) technologies are revolutionizing the way to explore the spatial
architecture of tissues. Currently, ST data analysis is often restricted to a single two …
architecture of tissues. Currently, ST data analysis is often restricted to a single two …
Gene expression cartography
Multiplexed RNA sequencing in individual cells is transforming basic and clinical life
sciences,,–. Often, however, tissues must first be dissociated, and crucial information about …
sciences,,–. Often, however, tissues must first be dissociated, and crucial information about …
High-resolution 3D spatiotemporal transcriptomic maps of develo** Drosophila embryos and larvae
M Wang, Q Hu, T Lv, Y Wang, Q Lan, R **ang, Z Tu… - Developmental Cell, 2022 - cell.com
Drosophila has long been a successful model organism in multiple biomedical fields. Spatial
gene expression patterns are critical for the understanding of complex pathways and …
gene expression patterns are critical for the understanding of complex pathways and …
Ultrasensitive proteome analysis using paramagnetic bead technology
In order to obtain a systems‐level understanding of a complex biological system, detailed
proteome information is essential. Despite great progress in proteomics technologies …
proteome information is essential. Despite great progress in proteomics technologies …
Germline Cas9 promoters with improved performance for homing gene drive
J Du, W Chen, X Jia, X Xu, E Yang, R Zhou… - Nature …, 2024 - nature.com
Gene drive systems could be a viable strategy to prevent pathogen transmission or suppress
vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR …
vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR …