This paper describes the substances of plant and marine origin that have anticancer
properties. The chemical structure of the molecules of these substances, their properties …

The concept of a scaffold concerns many aspects at different steps on the drug development
path. In medicinal chemistry, the choice of relevant “drug-likeness” scaffold is a starting point …

Cancer is a disorder that rigorously affects the human population worldwide. There is a
steady demand for new remedies to both treat and prevent this life-threatening sickness due …

Microtubule-targeting agents (MTAs) have demonstrated remarkable efficacy as antitumor,
antifungal, antiparasitic, and herbicidal agents, finding applications in the clinical, veterinary …

Microtubules are highly dynamic polymers of α, β-tubulin dimers which play an essential role
in numerous cellular processes such as cell proliferation and intracellular transport, making …

A series of benzoxazole-N-heterocyclic hybrids have been synthesized by a one-pot
strategy. Molecular docking study revealed that such compounds have the ability to inhibit …

Because of its wide spectrum of targets and biological activities, the oxazole ring is a
valuable heterocyclic scaffold in the design of new therapeutic agents with anticancer …

The growing interest in anticancer hybrids in the last few years has resulted in a great
number of reports on hybrid design, synthesis and bioevaluation. Many novel multi-target …

This study aimed to synthesize new thioderivative chalcones and analyze their impact on the
NF-κB, STAT3, EGFR and Nrf2 signaling pathways in colorectal cancer cells. Among the …

Research on compounds derived from, or inspired by, natural compounds as novel
anticancer agents has been a significantly focus in recent years. In this study, we reported …