[HTML][HTML] Cell death due to electroporation–a review

TB Napotnik, T Polajžer, D Miklavčič - Bioelectrochemistry, 2021 - Elsevier
Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

Gene transfer to plants by electroporation: methods and applications

II Ozyigit - Molecular Biology Reports, 2020 - Springer
Develo** gene transfer technologies enables the genetic manipulation of the living
organisms more efficiently. The methods used for gene transfer fall into two main categories; …

Extended focal ablation of localized prostate cancer with high-frequency irreversible electroporation: a nonrandomized controlled trial

H Wang, W Xue, W Yan, L Yin, B Dong, B He… - JAMA …, 2022 - jamanetwork.com
Importance Focal therapy of prostate cancer must balance the oncologic outcome and
functional outcome. High-frequency irreversible electroporation (H-FIRE) can destroy cancer …

Electroporation and cell killing by milli-to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation

E Gudvangen, V Kim, V Novickij, F Battista… - Scientific Reports, 2022 - nature.com
Ablation therapies aim at eradication of tumors with minimal impact on surrounding healthy
tissues. Conventional pulsed electric field (PEF) treatments cause pain and muscle …

Dynamics of cell death after conventional IRE and H-FIRE treatments

B Mercadal, N Beitel-White, KN Aycock… - Annals of biomedical …, 2020 - Springer
High-frequency irreversible electroporation (H-FIRE) has emerged as an alternative to
conventional irreversible electroporation (IRE) to overcome the issues associated with …

Characterization of conductivity changes during high-frequency irreversible electroporation for treatment planning

Y Zhao, S Bhonsle, S Dong, Y Lv, H Liu… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
For irreversible-electroporation (IRE)-based therapies, the underlying electric field
distribution in the target tissue is influenced by the electroporation-induced conductivity …

High-frequency irreversible electroporation for treatment of primary liver cancer: a proof-of-principle study in canine hepatocellular carcinoma

BR Partridge, TJ O'Brien, MF Lorenzo… - Journal of Vascular and …, 2020 - Elsevier
Purpose To determine the safety and feasibility of percutaneous high-frequency irreversible
electroporation (HFIRE) for primary liver cancer and evaluate the HFIRE-induced local …

First human trial of high-frequency irreversible electroporation therapy for prostate cancer

S Dong, H Wang, Y Zhao, Y Sun… - Technology in cancer …, 2018 - journals.sagepub.com
Irreversible electroporation, as a nonthermal therapy of prostate cancer, has been used in
clinic for several years. The mechanism of irreversible electroporation ablation is thermal …

Bipolar microsecond pulses and insulated needle electrodes for reducing muscle contractions during irreversible electroporation

C Yao, S Dong, Y Zhao, Y Lv, H Liu… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
Objective: To minimize the effect of muscle contractions during irreversible electroporation
(IRE), this paper attempts to research the ablation effect and muscle contractions by …

Effect of interphase and interpulse delay in high-frequency irreversible electroporation pulses on cell survival, membrane permeabilization and electrode material …

A Vižintin, J Vidmar, J Ščančar, D Miklavčič - Bioelectrochemistry, 2020 - Elsevier
To achieve high efficiency of electroporation and to minimize unwanted side effects, the
electric field parameters must be optimized. Recently, it was suggested that biphasic high …