[HTML][HTML] Chitosan-tripolyphosphate nanoparticles designed to encapsulate polyphenolic compounds for biomedical and pharmaceutical applications− A review

MC Di Santo, CL D'Antoni, APD Rubio, A Alaimo… - Biomedicine & …, 2021 - Elsevier
Plant-based polyphenols are natural compounds, present in fruits and vegetables. During
recent years, polyphenols have gained special attention due to their nutraceutical and …

Hepatoprotective effect of quercetin: From chemistry to medicine

S Miltonprabu, M Tomczyk, K Skalicka-Woźniak… - Food and Chemical …, 2017 - Elsevier
Liver diseases caused by viral hepatitis infections have a negative impact on global health.
Approximately 30 million people in the USA and 29 million people in the European Union …

Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes

C Dai, G Sharma, G Liu, J Shen, B Shao, Z Hao - Environmental Pollution, 2024 - Elsevier
Aflatoxins (AFTs), a type of mycotoxin mainly produced by Aspergillus parasiticus and
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …

Potential benefits and phytotoxicity of bulk and nano-chitosan on the growth, morphogenesis, physiology, and micropropagation of Capsicum annuum

G Asgari-Targhi, A Iranbakhsh, ZO Ardebili - Plant Physiology and …, 2018 - Elsevier
Concerning environmental issues of metal based-nanomaterials and increasing demand for
nano-based products; various strategies have been employed to find eco-friendly natural …

Protective effects of phenolics rich extract of ginger against Aflatoxin B1-induced oxidative stress and hepatotoxicity

AV Vipin, R Rao, NK Kurrey, AA KA… - Biomedicine & …, 2017 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is one of the predominant mycotoxin contaminant in food and
feed, causing oxidative stress and hepatotoxicity. Ginger phenolics have been reported for …

Cytotoxic and epigenetic effects of berberine-loaded chitosan/pectin nanoparticles on AGS gastric cancer cells: role of the miR-185-5p/KLF7 axis, DNMTs, and global …

E Babaeenezhad, M Rashidipour, Z Jangravi… - International Journal of …, 2024 - Elsevier
Poor bioavailability, solubility, and absorption of berberine (Ber) limit its widespread
application. Here, we formulated novel chitosan/pectin nanoparticles (NPs) loaded with Ber …

[HTML][HTML] Green synthesis of silymarin–chitosan nanoparticles as a new nano formulation with enhanced anti-fibrotic effects against liver fibrosis

AS Abdullah, IETE Sayed, AMA El-Torgoman… - International Journal of …, 2022 - mdpi.com
Background: Silymarin (SIL) has long been utilized to treat a variety of liver illnesses, but
due to its poor water solubility and low membrane permeability, it has a low oral …

[HTML][HTML] Acute aflatoxin B1–Induced hepatotoxicity alters gene expression and disrupts lipid and lipoprotein metabolism in rats

OA Rotimi, SO Rotimi, CU Duru, OJ Ebebeinwe… - Toxicology reports, 2017 - Elsevier
In this study, alterations in lipid metabolism associated with acute aflatoxin B1 (AFB1)
induced hepatotoxicity and gene expression changes underlying these effects were …

Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats …

SE Owumi, CE Irozuru, UO Arunsi, AK Oyelere - Toxicon, 2022 - Elsevier
Aflatoxicosis can induce largescale toxicities in predisposed populations. Food fortification
with adequate antioxidant sources may reduce the toxic burden from aflatoxicosis. We …