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Ecology and evolution of Mycobacterium tuberculosis
S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …
The causative agents of TB are a group of closely related bacteria known as the …
Towards a genomics-informed, real-time, global pathogen surveillance system
Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
[HTML][HTML] Elevated rates of horizontal gene transfer in the industrialized human microbiome
Industrialization has impacted the human gut ecosystem, resulting in altered microbiome
composition and diversity. Whether bacterial genomes may also adapt to the …
composition and diversity. Whether bacterial genomes may also adapt to the …
[HTML][HTML] Reconstruction of ancient microbial genomes from the human gut
Loss of gut microbial diversity,,,,–in industrial populations is associated with chronic
diseases, underscoring the importance of studying our ancestral gut microbiome. However …
diseases, underscoring the importance of studying our ancestral gut microbiome. However …
Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes
Background: The Global Typhoid Genomics Consortium was established to bring together
the typhoid research community to aggregate and analyse Salmonella enterica serovar …
the typhoid research community to aggregate and analyse Salmonella enterica serovar …
Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients
Background. Klebsiella pneumoniae is an opportunistic pathogen and leading cause of
hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk …
hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk …
Ancient pathogen genomics as an emerging tool for infectious disease research
Over the past decade, a genomics revolution, made possible through the development of
high-throughput sequencing, has triggered considerable progress in the study of ancient …
high-throughput sequencing, has triggered considerable progress in the study of ancient …
The distribution of bacterial doubling times in the wild
Generation time varies widely across organisms and is an important factor in the life cycle,
life history and evolution of organisms. Although the doubling time (DT) has been estimated …
life history and evolution of organisms. Although the doubling time (DT) has been estimated …
Widespread extinctions of co-diversified primate gut bacterial symbionts from humans
JG Sanders, DD Sprockett, Y Li, D Mjungu… - Nature …, 2023 - nature.com
Humans and other primates harbour complex gut bacterial communities that influence
health and disease, but the evolutionary histories of these symbioses remain unclear. This is …
health and disease, but the evolutionary histories of these symbioses remain unclear. This is …
Genomic history of the seventh pandemic of cholera in Africa
FX Weill, D Domman, E Njamkepo, C Tarr, J Rauzier… - Science, 2017 - science.org
The seventh cholera pandemic has heavily affected Africa, although the origin and
continental spread of the disease remain undefined. We used genomic data from 1070 …
continental spread of the disease remain undefined. We used genomic data from 1070 …