Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …
releasing activity. This activity is mediated by the activation of the so-called GH …
Ghrelin—a hormone with multiple functions
Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
Ghrelin is an acyl-peptide gastric hormone acting on the pituitary and hypothalamus to
stimulate growth hormone (GH) release, adiposity, and appetite. Ghrelin endocrine activities …
stimulate growth hormone (GH) release, adiposity, and appetite. Ghrelin endocrine activities …
Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ
A Inui, A Asakawa, C Y. Bowers… - The FASEB …, 2004 - Wiley Online Library
Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …
Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial
NM Neary, CJ Small, AM Wren, JL Lee… - The Journal of …, 2004 - academic.oup.com
There is a pressing need for more effective appetite-stimulatory therapies for many patient
groups including those with cancer. We have previously demonstrated that the gastric …
groups including those with cancer. We have previously demonstrated that the gastric …
Ghrelin in the regulation of body weight and metabolism
TR Castaneda, J Tong, R Datta, M Culler… - Frontiers in …, 2010 - Elsevier
Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …
Exercise-induced suppression of acylated ghrelin in humans
Ghrelin is an orexigenic hormone secreted from endocrine cells in the stomach and other
tissues. Acylation of ghrelin is essential for appetite regulation. Vigorous exercise induces …
tissues. Acylation of ghrelin is essential for appetite regulation. Vigorous exercise induces …
Ghrelin and Des-Octanoyl Ghrelin Promote Adipogenesis Directly in Vivo by a Mechanism Independent of the Type 1a Growth Hormone Secretagogue Receptor
NM Thompson, DAS Gill, R Davies, N Loveridge… - …, 2004 - academic.oup.com
Ghrelin promotes fat accumulation, despite potent stimulation of the lipolytic hormone, GH.
The function of the major circulating isoform of ghrelin, des-octanoyl ghrelin, is unclear …
The function of the major circulating isoform of ghrelin, des-octanoyl ghrelin, is unclear …
Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity
G Muccioli, M Tschöp, M Papotti, R Deghenghi… - European journal of …, 2002 - Elsevier
Ghrelin, a 28-amino acid acylated peptide predominantly produced by the stomach, displays
strong growth hormone (GH)-releasing activity mediated by the hypothalamus–pituitary GH …
strong growth hormone (GH)-releasing activity mediated by the hypothalamus–pituitary GH …
Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors
M Volante, E AllÌa, P Gugliotta, A Funaro… - The Journal of …, 2002 - academic.oup.com
Ghrelin is a novel gastrointestinal hormone produced by rat and human gastric X-like
neuroendocrine cells, which strongly stimulates GH secretion and influences energy …
neuroendocrine cells, which strongly stimulates GH secretion and influences energy …