The emergence of modern photocatalysis, characterized by mildness and selectivity, has
significantly spurred innovative late-stage C–H functionalization approaches that make use …

Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or
diversification of novel molecular entities with improved physicochemical or biological …

1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Hypervalent iodine (III) compounds have found wide application in modern organic
chemistry as environmentally friendly reagents and catalysts. Hypervalent iodine reagents …

Azines, such as pyridines, quinolines, pyrimidines, and pyridazines, are widespread
components of pharmaceuticals. Their occurrence derives from a suite of physiochemical …

The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool
to speed up the identification of structure–activity relationships (SARs) and to optimize …

Alkyl radicals are key intermediates in organic synthesis. Their classic generation from alkyl
halides has a severe drawback due to the employment of toxic tin hydrides to the point that …

Conspectus The radical-mediated C–H functionalization of pyridines has attracted
considerable attention as a powerful tool in synthetic chemistry for the direct …

Reactions that involve the addition of carbon‐centered radicals to basic heteroarenes,
followed by formal hydrogen atom loss, have become widely known as Minisci‐type …

Transition metal-catalyzed C–H bond functionalizations have been the focus of intensive
research over the last decades for the formation of C–C bonds from unfunctionalized arenes …