During the past decades, better understanding of relapsing-remitting multiple sclerosis
disease mechanisms have led to the development of several disease-modifying therapies …

Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. Current treatments are very effective in reducing the neuroinflammatory attack, but …

Objective In multiple sclerosis (MS), cerebral gray matter (GM) atrophy correlates more
strongly than white matter (WM) atrophy with disability. The corresponding relationships in …

Multiple sclerosis is the major inflammatory condition affecting the central nervous system
(CNS) and is characterised by disseminated focal immune-mediated demyelination …

ABSTRACT BACKGROUND AND PURPOSE Spinal cord atrophy (SCA) is an important
emerging outcome measure in multiple sclerosis (MS); however, there is limited consensus …

Background: Spinal cord pathology is an important substrate for long-term disability in
multiple sclerosis (MS). Objective: To investigate longitudinal changes in spinal cord lesions …

The spinal cord is frequently affected in multiple sclerosis (MS), causing motor, sensory and
autonomic dysfunction. A number of pathological abnormalities, including demyelination …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system that affects millions of patients worldwide. The current disease-modifying therapies …

Objective To examine the temporal evolution of spinal cord (SC) atrophy in multiple sclerosis
(MS), and its association with clinical progression in a large MS cohort. Methods A total of …