Drug-induced long QT syndrome (diLQTS) and congenital LQTS (cLQTS) share many
features, and both syndromes can result in life-threatening torsades de pointes (TdP). Our …

Background Electronic health record (EHR) alert fatigue, while widely recognized as a
concern nationally, lacks a corresponding comprehensive mitigation plan. Objectives The …

Clinical decision support systems (CDSS) are computer systems designed to impact
clinician decision making about individual patients at the point in time that these decisions …

Objective To develop and evaluate a data-driven process to generate suggestions for
improving alert criteria using explainable artificial intelligence (XAI) approaches. Methods …

Since its initial description by Jervell and Lange-Nielsen in 1957, the congenital long QT
syndrome (LQTS) has been the most investigated cardiac ion channelopathy. Although …

Objectives To assess the evidence of the effectiveness of different categories of interruptive
medication prescribing alerts to change prescriber behavior and/or improve patient …

Background Computerised decision support (CDS) based on trustworthy clinical guidelines
is a key component of a learning healthcare system. Research shows that the effectiveness …

A CDSS generates a high number of inappropriate alerts that interrupt the clinical workflow.
As a result, clinicians silence, disable, or ignore alerts, thereby undermining patient safety …

Background. Electronic alerts (e-alerts) for acute kidney injury (AKI) in hospitalized patients
are increasingly being implemented; however, their impact on outcomes remains uncertain …

Purpose Current uses of medication-related clinical decision support (CDS) and
recommendations for improving these systems are reviewed. Summary Using a systematic …