Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …

Unfavorable phenotypes characterized by low immunogenicity and acidity within the tumor
microenvironment (TME) contribute to immunosuppression and therapeutic resistance …

The monolayer (two-dimensional or 2D) cell culture, while widely used, lacks fidelity in
replicating vital cell interactions seen in vivo, leading to a shift toward three-dimensional …

Purpose In the develo** field of nano-materials synthesis, copper oxide nanoparticles
(NPs) are deemed to be one of the most significant transition metal oxides because of their …

Plasma membrane damage (PMD) occurs in all cell types due to environmental perturbation
and cell-autonomous activities. However, cellular outcomes of PMD remain largely unknown …

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to low
therapeutic response rates and poor prognoses. Majority of patients present with symptoms …

Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

The tumour microenvironment presents many challenges in the development and evaluation
of new anti-cancer therapeutics. Enhanced understanding of the unique metabolic …

The 2020 global cancer registry has ranked breast cancer (BCa) as the most commonly
diagnosed type of cancer and the most common cause of cancer-related deaths in women …

Background: Retention after orthodontic tooth movement (OTM) is essential to prevent
relapse. This study examined the effects of a fixed orthodontic device and Nano Calcium …