REV-ERB and ROR nuclear receptors as drug targets
The nuclear receptors REV-ERB (consisting of REV-ERBα and REV-ERBβ) and retinoic acid
receptor-related orphan receptors (RORs; consisting of RORα, RORβ and RORγ) are …
receptor-related orphan receptors (RORs; consisting of RORα, RORβ and RORγ) are …
Molecular mechanisms of adipogenesis: the anti-adipogenic role of AMP-activated protein kinase
Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
Chinese herbal medicines: The modulator of nonalcoholic fatty liver disease targeting oxidative stress
P Gong, H Long, Y Guo, Z Wang, W Yao, J Wang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Plants are a natural treasure trove; their secondary
metabolites participate in several pharmacological processes, making them a crucial …
metabolites participate in several pharmacological processes, making them a crucial …
Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds
Obesity is growing at an alarming rate, which is characterized by increased adipose tissue. It
increases the probability of many health complications, such as diabetes, arthritis, cardiac …
increases the probability of many health complications, such as diabetes, arthritis, cardiac …
Saikosaponin A and D inhibit adipogenesis via the AMPK and MAPK signaling pathways in 3T3-L1 adipocytes
SH Lim, HS Lee, HK Han, CI Choi - International journal of molecular …, 2021 - mdpi.com
Obesity is a lipid metabolism disorder caused by genetic, medicinal, nutritional, and other
environmental factors. It is characterized by a complex condition of excess lipid …
environmental factors. It is characterized by a complex condition of excess lipid …
Oleanolic, ursolic, and betulinic acids as food supplements or pharmaceutical agents for type 2 diabetes: promise or illusion?
Oleanolic (OA), ursolic (UA), and betulinic (BA) acids are three triterpenic acids (TAs) with
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …
[HTML][HTML] Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression …
T Li, L Zhang, C **, Y **ong, YY Cheng… - Biomedicine & …, 2020 - Elsevier
Objectives Pomegranate flower is a kind of uygur medicine with anti-type 2 diabetes, anti-
lipid, anti-inflammation, anti-oxidation. We investigated the effect of pomegranate flower …
lipid, anti-inflammation, anti-oxidation. We investigated the effect of pomegranate flower …
Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy
The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …
Ursolic acid and related analogues: triterpenoids with broad health benefits
Ursolic acid (UA) is a well-studied natural pentacyclic triterpenoid found in herbs, fruit and a
number of traditional Chinese medicinal plants. UA has a broad range of biological activities …
number of traditional Chinese medicinal plants. UA has a broad range of biological activities …
Potential of natural products in the inhibition of adipogenesis through regulation of PPARγ expression and/or its transcriptional activity
Obesity is a global health problem characterized as an increase in the mass of adipose
tissue. Adipogenesis is one of the key pathways that increases the mass of adipose tissue …
tissue. Adipogenesis is one of the key pathways that increases the mass of adipose tissue …