Importance: Gliomas, tumors of the central nervous system, are classically diagnosed
through invasive surgical biopsy and subsequent histopathological study. Innovations in …

Chemical exchange saturation transfer (CEST) MRI has become a promising technique to
assay target proteins and metabolites through their exchangeable protons, noninvasively …

Non-invasive imaging methods for detecting intratumoural viral spread and host responses
to oncolytic virotherapy are either slow, lack specificity or require the use of radioactive or …

Purpose Calculation of sophisticated MR contrasts often requires complex mathematical
modeling. Data evaluation is computationally expensive, vulnerable to artifacts, and often …

Purpose To optimize and apply deep neural network based CEST (deepCEST) and
apparent exchange dependent‐relaxation (deepAREX) for imaging the mouse brain with …

The current study aims to assign and estimate the total creatine (tCr) signal contribution to
the Z‐spectrum in mouse brain at 11.7 T. Creatine (Cr), phosphocreatine (PCr) and protein …

Purpose To develop a steady‐state saturation with radial readout chemical exchange
saturation transfer (starCEST) for acquiring CEST images at 3 Tesla (T). The polynomial …

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects
molecules in their natural forms in a sensitive and non-invasive manner. This makes it a …

High image signal–to–noise ratio (SNR) is required to reliably detect the inherently small
chemical exchange saturation transfer (CEST) effects in vivo. In this study, it was …

Purpose Chemical exchange saturation transfer (CEST) MRI is promising for detecting dilute
metabolites and microenvironment properties, which has been increasingly adopted in …