Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention

CA Massey, LP Sowers, BJ Dlouhy… - Nature Reviews …, 2014 - nature.com
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients
with refractory epilepsy, with an estimated 35% lifetime risk in this patient population. There …

Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms

R Surges, RD Thijs, HL Tan, JW Sander - Nature Reviews Neurology, 2009 - nature.com
Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death directly
related to epilepsy, and most frequently occurs in people with chronic epilepsy. The main …

A systematic review and meta‐analysis of heart rate variability in epilepsy and antiepileptic drugs

PA Lotufo, L Valiengo, IM Bensenor, AR Brunoni - Epilepsia, 2012 - Wiley Online Library
Purpose: Epilepsy is associated with near‐fatal and fatal arrhythmias, and sudden
unexpected death in epilepsy (SUDEP) is partly related to cardiac events. Dysfunction of the …

RMSSD, a measure of vagus-mediated heart rate variability, is associated with risk factors for SUDEP: the SUDEP-7 Inventory

CM DeGiorgio, P Miller, S Meymandi, A Chin, J Epps… - Epilepsy & Behavior, 2010 - Elsevier
OBJECTIVE: The goal of this study was to determine if specific measures of heart rate
variability (HRV) are associated with the total score on a new seven-item inventory for …

[HTML][HTML] Cardiac changes in epilepsy

K Jansen, L Lagae - Seizure, 2010 - Elsevier
Epilepsy and seizures can have a dramatic effect on the autonomic nervous system by
involvement of the central autonomic control centers. The peri-ictal changes can lead to …

Sudden unexpected death in epilepsy: mechanisms, prevalence, and prevention

R Surges, JW Sander - Current opinion in neurology, 2012 - journals.lww.com
Novel clinical features may help to define better the individual risk of SUDEP. Potentially
therapeutic strategies including pharmacological modulation of respiratory arrest and …

[HTML][HTML] Sudden unexpected death in epilepsy: The neuro-cardio-respiratory connection

TA Manolis, AA Manolis, H Melita, AS Manolis - Seizure, 2019 - Elsevier
Sudden unexpected death in epilepsy (SUDEP) is the major cause of epilepsy-related
premature mortality which targets preferentially younger people. Its etiology remains …

[BOOK][B] Heart rate variability (HRV) signal analysis: clinical applications

MV Kamath, M Watanabe, A Upton - 2016 - books.google.com
This cutting-edge reference examines how beat-to-beat variations in heart rate and blood
pressure provide a window into the health of the autonomic nervous system. The book …

Who to target in sudden unexpected death in epilepsy prevention and how? Risk factors, biomarkers, and intervention study designs

T Tomson, R Surges, R Delamont, S Haywood… - …, 2016 - Wiley Online Library
The risk of dying suddenly and unexpectedly is increased 24‐to 28‐fold among young
people with epilepsy compared to the general population, but the incidence of sudden …

Music therapy in medical and neurological rehabilitation settings

AK Leins, R Spintge - 2008 - academic.oup.com
This article discusses music therapy in medical and neurological rehabilitation settings.
Neurologic music therapy encompasses evidence-based methods of the functional …