Meningioma: a review of epidemiology, pathology, diagnosis, treatment, and future directions

C Ogasawara, BD Philbrick, DC Adamson - Biomedicines, 2021 - mdpi.com
Meningiomas are the most common intracranial tumor, making up more than a third of all
primary central nervous system (CNS) tumors. They are mostly benign tumors that can be …

[HTML][HTML] Current understanding of neurofibromatosis type 1, 2, and schwannomatosis

R Tamura - International journal of molecular sciences, 2021 - mdpi.com
Neurofibromatosis (NF) is a neurocutaneous syndrome characterized by the development of
tumors of the central or peripheral nervous system including the brain, spinal cord, organs …

Meningioma: a review of clinicopathological and molecular aspects

K Huntoon, AMS Toland, S Dahiya - Frontiers in oncology, 2020 - frontiersin.org
Meningiomas are the most the common primary brain tumors in adults, representing
approximately a third of all intracranial neoplasms. They classically are found to be more …

An update on the CNS manifestations of neurofibromatosis type 2

S Coy, R Rashid, A Stemmer-Rachamimov… - Acta …, 2020 - Springer
Neurofibromatosis type II (NF2) is a tumor predisposition syndrome characterized by the
development of distinctive nervous system lesions. NF2 results from loss-of-function …

Neurofibromatosis: a review of NF1, NF2, and schwannomatosis

JL Kresak, M Walsh - Journal of pediatric genetics, 2016 - thieme-connect.com
The neurofibromatoses are a heterogeneous group of hereditary cancer syndromes that
lead to tumors of the central and peripheral nervous systems, as well as other organ …

Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas

MJ Smith, J O'Sullivan, SS Bhaskar, KD Hadfield… - Nature …, 2013 - nature.com
One-third of all primary central nervous system tumors in adults are meningiomas. Rarely,
meningiomas occur at multiple sites, usually occurring in individuals with type 2 …

Genetic Severity Score predicts clinical phenotype in NF2

D Halliday, B Emmanouil, P Pretorius… - Journal of medical …, 2017 - jmg.bmj.com
​ Background The clinical severity of disease in neurofibromatosis type 2 (NF2) is variable.
Patients affected with a constitutional truncating NF2 mutation have severe disease, while …

The genetic landscape and possible therapeutics of neurofibromatosis type 2

MA Ghalavand, A Asghari, M Farhadi… - Cancer Cell …, 2023 - Springer
Abstract Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development
of multiple benign tumors in the nervous system. The most common tumors associated with …

Cancer and central nervous system tumor surveillance in pediatric neurofibromatosis 2 and related disorders

DGR Evans, H Salvador, VY Chang, A Erez… - Clinical Cancer …, 2017 - aacrjournals.org
The neurofibromatoses consist of at least three autosomal-dominant inherited disorders:
neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis. For …

Neurofibromatosis type 2: presentation, major complications, and management, with a focus on the pediatric age group

S Ardern-Holmes, G Fisher… - Journal of child …, 2017 - journals.sagepub.com
Neurofibromatosis type 2 (NF2) is a rare autosomal dominant disorder (incidence 1: 33 000-
40 000) characterized by formation of central nervous system tumors, due to mutation in the …