Microfluidic fabrication of microparticles for biomedical applications
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …
enabling fabrication of advanced microparticles with precisely tunable structures and …
A comprehensive review on 3D tissue models: biofabrication technologies and preclinical applications
R **e, V Pal, Y Yu, X Lu, M Gao, S Liang, M Huang… - Biomaterials, 2024 - Elsevier
The limitations of traditional two-dimensional (2D) cultures and animal testing, when it
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …
[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
In vitro strategies to vascularize 3D physiologically relevant models
A Dellaquila, C Le Bao, D Letourneur… - Advanced …, 2021 - Wiley Online Library
Vascularization of 3D models represents a major challenge of tissue engineering and a key
prerequisite for their clinical and industrial application. The use of prevascularized models …
prerequisite for their clinical and industrial application. The use of prevascularized models …
Applications of biomaterials in 3D cell culture and contributions of 3D cell culture to drug development and basic biomedical research
The process of evaluating the efficacy and toxicity of drugs is important in the production of
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …
Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips
Recent advancements in digital-light-processing (DLP)-based bioprinting and hydrogel
engineering have enabled novel developments in organs-on-chips. In this work, we …
engineering have enabled novel developments in organs-on-chips. In this work, we …
Design and fabrication of drug‐delivery systems toward adjustable release profiles for personalized treatment
Advanced polymeric controlled delivery systems are designed to effectively treat chronic
diseases by adjusting the temporal profile of drug release. Most conventional controlled …
diseases by adjusting the temporal profile of drug release. Most conventional controlled …
Microfluidic skin‐on‐a‐chip models: Toward biomimetic artificial skin
The role of skin in the human body is indispensable, serving as a barrier, moderating
homeostatic balance, and representing a pronounced endpoint for cosmetics and …
homeostatic balance, and representing a pronounced endpoint for cosmetics and …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …