Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

Damage-associated molecular patterns in viral infection: potential therapeutic targets

H Tian, Q Liu, X Yu, Y Cao, X Huang - Critical Reviews in …, 2024 - Taylor & Francis
Frequent viral infections leading to infectious disease outbreaks have become a significant
global health concern. Fully elucidating the molecular mechanisms of the immune response …

IRF3 inhibits inflammatory signaling pathways in macrophages to prevent viral pathogenesis

S Chakravarty, M Varghese, S Fan, RT Taylor… - Science …, 2024 - science.org
Viral inflammation contributes to pathogenesis and mortality during respiratory virus
infections. IRF3, a critical component of innate antiviral immune responses, interacts with pro …

Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling …

H Zhao, P Wang, X Wang, W Du, HH Yang… - Cardiovascular …, 2023 - academic.oup.com
Aims Systemic inflammation occurs commonly during many human disease settings and
increases vascular permeability, leading to organ failure, and lethal outcomes. Lipocalin 10 …

Chemical Composition of Thyme (Thymus vulgaris) Extracts, Potential Inhibition of SARS-CoV-2 Spike Protein–ACE2 Binding and ACE2 Activity, and Radical …

Y Yao, M Whent, Y Li, Z Liu, P Pehrsson… - Journal of Agricultural …, 2023 - ACS Publications
Water and ethanol extracts of dried thyme (Thymus vulgaris) were analyzed for chemical
composition, inhibition of the SARS-CoV-2 spike protein–ACE2 interaction, inhibition of …

[HTML][HTML] Myricetin inhibits Micropterus salmoides rhabdovirus infection by dam** inflammation through the NF-κB pathway

Z Wang, P Deng, Z Gu, L Li, J Yuan - Aquaculture and Fisheries, 2023 - Elsevier
Largemouth bass have been plagued by diseases elicited by bacteria, parasites, and
viruses, particularly viral diseases, which have caused significant economic losses in recent …

Non-transcriptional IRF7 interacts with NF-κB to inhibit viral inflammation

S Fan, S Popli, S Chakravarty, R Chakravarti… - Journal of Biological …, 2024 - ASBMB
Interferon (IFN) regulatory factors (IRF) are key transcription factors in cellular antiviral
responses. IRF7, a virus-inducible IRF, expressed primarily in myeloid cells, is required for …

Validation of monocyte CD169 expression as a valuable rapid diagnostic marker of SARS-CoV-2 and other acute viral infections

C Pratesi, R De Rosa, E Pivetta… - American Journal of …, 2024 - academic.oup.com
Objectives Acute infectious diseases are some of the most common reasons for receiving
medical care, and analysis of the host immune response is an attractive approach for their …

Pralatrexate inhibited the replication of varicella zoster virus and vesicular stomatitis virus: An old dog with new tricks

J Wu, Y Cai, N Jiang, Y Qian, R Lyu, Q You, F Zhang… - Antiviral Research, 2024 - Elsevier
Varicella zoster virus (VZV) is associated with herpes zoster (HZ) or herpes zoster
ophthalmicus (HZO). All antiviral agents currently licensed for the management of VZV …

Repositioned Natural Compounds and Nanoformulations: A Promising Combination to Counteract Cell Damage and Inflammation in Respiratory Viral Infections

A Mariano, I Bigioni, M Marchetti, A Scotto d'Abusco… - Molecules, 2023 - mdpi.com
Respiratory viral diseases are among the most important causes of disability, morbidity, and
death worldwide. Due to the limited efficacy or side effects of many current therapies and the …