Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

Hypersensitivity reactions (HSRs) to chemotherapy drugs, such as taxanes and platins, and
to monoclonal antibodies limit their therapeutic use due to the severity of some reactions …

Reactive oxygen species (ROS) are molecules involved in signal transduction pathways
with both beneficial and detrimental effects on human cells. ROS are generated by many …

Hypersensitivity reactions (HSRs) to platinum drugs are increasing due to their extensive
use in a wide variety of malignancies and the repeated exposures in patients with increased …

Background Oxaliplatin hypersensitivity (OXS) presents a challenge in the treatment of
oxaliplatin-sensitive malignancies. Objective To analyze patient characteristics of patients …

Background Oxaliplatin causes a wider variety of immediate hypersensitivity reactions than
do other platin-based chemotherapeutics. Some resemble type 1 reactions that respond to …

Hypersensitivity reactions (HSRs) to antineoplastic drugs are increasing due to the
expanding use of classical and new drugs in a wide variety of malignancies. Purpose of …

Rectal cancer, along with colon cancer, is the second leading cause of cancer-related
deaths in the US Up to a quarter of patients have metastatic disease at diagnosis and 40 …

Drug hypersensitivity reactions (HSR) are adverse events resembling allergy which occur at
therapeutic doses. Both anticancer chemotherapeutics and monoclonal antibodies have the …

It is estimated that each year more than 10 million people worldwide are diagnosed with
cancer, and its incidence is constantly increasing not only in industrialized countries but also …