In ARDS patients, the change from supine to prone position generates a more even
distribution of the gas–tissue ratios along the dependent–nondependent axis and a more …

Prone positioning was first proposed in the 1970s as a method to improve gas exchange in
ARDS. Subsequent observations of dramatic improvement in oxygenation with simple …

Background The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting …

Background The COVID-19 pandemic is challenging advanced health systems, which are
dealing with an overwhelming number of patients in need of intensive care for respiratory …

Importance Adjusting positive end-expiratory pressure (PEEP) to offset pleural pressure
might attenuate lung injury and improve patient outcomes in acute respiratory distress …

As with most medical and pharmacologic interventions, mechanical ventilation must be
titrated within a therapeutic window, providing the required lifesustaining support while …

OBJECTIVES: Prone positioning allows to improve oxygenation and decrease mortality rate
in COVID-19–associated acute respiratory distress syndrome (C-ARDS). However, the …

In the prone position, computed tomography scan densities redistribute from dorsal to
ventral as the dorsal region tends to reexpand while the ventral zone tends to collapse …

Purpose Prone positioning (PP) improves oxygenation and outcome of patients with acute
respiratory distress syndrome undergoing invasive ventilation. We evaluated feasibility and …

The pathophysiological mechanisms by which mechanical ventilation can contribute to lung
injury, termed “ventilator-induced lung injury”(VILI), is increasingly well understood.“ …