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The medicinal chemistry of piperazines: A review
M Faizan, R Kumar, A Mazumder… - Chemical Biology & …, 2024 - Wiley Online Library
The versatile basic structure of piperazine allows for the development and production of
newer bioactive molecules that can be used to treat a wide range of diseases. Piperazine …
newer bioactive molecules that can be used to treat a wide range of diseases. Piperazine …
Synthetic Protocols, Structural Activity Relationship, and Biological Activity of Piperazine and its Derivatives
M Faizan, R Kumar, A Mazumder… - Medicinal …, 2024 - benthamdirect.com
The versatile basic structure of piperazine allows for the development and production of
newer bioactive molecules that can be used to treat a wide range of diseases. Piperazine …
newer bioactive molecules that can be used to treat a wide range of diseases. Piperazine …
New piperazine-based bis(thieno[2,3-b]pyridine) and bis(pyrazolo[3,4-b]pyridine) hybrids linked to benzofuran units: Synthesis and in vitro screening of potential …
Two series of piperazine-based bis (thieno [2, 3-b] pyridines) and bis (pyrazolo [3, 4-b]
pyridines) were prepared, in good yields, utilizing the appropriate bis (pyridinethione). The …
pyridines) were prepared, in good yields, utilizing the appropriate bis (pyridinethione). The …
Regioselective synthesis and theoretical calculations of Bis (pyrido [2′, 3′: 3, 4] pyrazolo [1, 5-a] pyrimidines) linked to benzofuran units via piperazine spacer: A …
Bis (enaminone), linked to benzofuran units via piperazine spacer, was prepared and used
as a key intermediate in this study. It reacted for 8 h at reflux with two equivalents of 2 …
as a key intermediate in this study. It reacted for 8 h at reflux with two equivalents of 2 …
Sulfonamide‐β‐lactam Hybrids Incorporating the Piperazine Moiety as Potential Antiinflammatory Agent with Promising Antibacterial Activity
Several monocyclic β‐lactams have been synthesized via a [2+ 2] ketene–imine
cycloaddition reaction (Staudinger reaction) and evaluated for their biological activities. The …
cycloaddition reaction (Staudinger reaction) and evaluated for their biological activities. The …
One-Pot Synthesis of Some New Phthalazine-Piperazine-1, 2, 4-Oxadiazole Hybrids: Anticancer Evaluation, Molecular Docking and ADMET Studies
R Samala, SK Nukala, NS Thirukovela… - Polycyclic Aromatic …, 2023 - Taylor & Francis
We herein, described the synthesis of some new phthalazine-piperazine-1, 2, 4-oxadiazole
hybrids (4a–n). All the synthesized compounds were evaluated for their in vitro anti-cancer …
hybrids (4a–n). All the synthesized compounds were evaluated for their in vitro anti-cancer …
[PDF][PDF] Develo** an M3 Antagonist for Molecular Imaging of Muscarinic Acetylcholine Receptors in Breast Cancer
MA Boateng - 2021 - era.library.ualberta.ca
The lack of the three targeted receptors, estrogen, progesterone, and the human epidermal
growth factor receptor 2, causes difficulty in treating triple negative type cancers. Most often …
growth factor receptor 2, causes difficulty in treating triple negative type cancers. Most often …