Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …
persistent chronic immune activation and inflammation. This condition is the result of several …
[HTML][HTML] Immunological approaches to HIV cure
Combination antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV)
infection has proven remarkably successful–for those who can access and afford it–yet HIV …
infection has proven remarkably successful–for those who can access and afford it–yet HIV …
Immunology of EBV-related lymphoproliferative disease in HIV-positive individuals
P Shindiapina, EH Ahmed, A Mozhenkova… - Frontiers in …, 2020 - frontiersin.org
Epstein-Bar virus (EBV) can directly cause lymphoproliferative disease (LPD), including
AIDS-defining lymphomas such as Burkitt's lymphoma and other non-Hodgkin lymphomas …
AIDS-defining lymphomas such as Burkitt's lymphoma and other non-Hodgkin lymphomas …
Individuals with higher CD4/CD8 ratio exhibit increased risk of acute respiratory distress syndrome and in-hospital mortality during acute SARS-CoV-2 infection
A Pascual-Dapena, JJ Chillaron, G Llauradó… - Frontiers in …, 2022 - frontiersin.org
Background CD4/CD8 ratio has been used as a quantitative prognostic risk factor in patients
with viral infections. This study aims to assess the association between in-hospital mortality …
with viral infections. This study aims to assess the association between in-hospital mortality …
(5R)-5-hydroxytriptolide for HIV immunological non-responders receiving ART: a randomized, double-blinded, placebo-controlled phase II study
W Cao, X Liu, Y Han, X Song, L Lu, X Li… - The Lancet Regional …, 2023 - thelancet.com
Background Therapeutic approaches to HIV-suppressed immunological non-responders
(INRs) remain unsettled. We previously reported efficacy of Chinese herbal Tripterygium …
(INRs) remain unsettled. We previously reported efficacy of Chinese herbal Tripterygium …
Increased biomarkers of cardiovascular risk in HIV-1 viremic controllers and low persistent inflammation in elite controllers and art-suppressed individuals
HIV controllers (HICs) are models of HIV functional cure, although some studies have shown
persistent inflammation and increased rates of atherosclerosis in HICs. Since immune …
persistent inflammation and increased rates of atherosclerosis in HICs. Since immune …
HCV cure with direct-acting antivirals improves liver and immunological markers in HIV/HCV-coinfected patients
Ó Brochado-Kith, I Martínez, J Berenguer… - Frontiers in …, 2021 - frontiersin.org
Hepatitis C virus (HCV) cure after all-oral direct-acting antiviral (DAA) therapy greatly
improves the liver and immune system. We aimed to assess the impact of this HCV …
improves the liver and immune system. We aimed to assess the impact of this HCV …
PSGL-1, a Strategic Biomarker for Pathological Conditions in HIV Infection: A Hypothesis Review
SD Zaongo, Y Chen - Viruses, 2023 - mdpi.com
P-selectin glycoprotein ligand-1 (PSGL-1) has been established to be a cell adhesion
molecule that is involved in the cellular rolling mechanism and the extravasation cascade …
molecule that is involved in the cellular rolling mechanism and the extravasation cascade …
Antigen presenting cells link the female genital tract microbiome to mucosal inflammation, with hormonal contraception as an additional modulator of inflammatory …
EH Byrne, M Farcasanu, SM Bloom, N Xulu… - Frontiers in cellular …, 2021 - frontiersin.org
The microbiome of the female genital tract (FGT) is closely linked to reproductive health
outcomes. Diverse, anaerobe-dominated communities with low Lactobacillus abundance …
outcomes. Diverse, anaerobe-dominated communities with low Lactobacillus abundance …
Immunological and senescence biomarker profiles in patients after spontaneous clearance of hepatitis C virus: gender implications for long-term health risk
Background About 25% of patients with acute hepatitis C virus (HCV) infection show
spontaneous clearance within the first six months of infection but may remain at risk of …
spontaneous clearance within the first six months of infection but may remain at risk of …