Hyperinsulinemia and its pivotal role in aging, obesity, type 2 diabetes, cardiovascular disease and cancer

JA Janssen - International journal of molecular sciences, 2021 - mdpi.com
For many years, the dogma has been that insulin resistance precedes the development of
hyperinsulinemia. However, recent data suggest a reverse order and place …

Bisphenol A: Food exposure and impact on human health

S Almeida, A Raposo… - … reviews in food …, 2018 - Wiley Online Library
Bisphenol A (BPA) is an industrial compound used extensively to produce synthetic
polymers, such as epoxy resins, which are incorporated into the inner coating of metal cans …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Glyphosate potentiates insulin resistance in skeletal muscle through the modulation of IRS-1/PI3K/Akt mediated mechanisms: an in vivo and in silico analysis

S Jayaraman, K Krishnamoorthy, M Prasad… - International Journal of …, 2023 - Elsevier
Herbicides have been linked to a higher risk of develo** diabetes. Certain herbicides also
operate as environmental toxins. Glyphosate is a popular and extremely effective herbicide …

Association of urinary concentrations of bisphenols with type 2 diabetes mellitus: a case-control study

Y Duan, Y Yao, B Wang, L Han, L Wang, H Sun… - Environmental …, 2018 - Elsevier
Bisphenols, as synthetic chemicals, have been widely detected in environmental and human
samples. Epidemiological studies have reported relationships between bisphenol A (BPA) …

Serum concentrations of bisphenol A and its alternatives in elderly population living around e-waste recycling facilities in China: Associations with fasting blood …

S Song, Y Duan, T Zhang, B Zhang, Z Zhao… - Ecotoxicology and …, 2019 - Elsevier
In the present study, concentrations of bisphenol A (BPA) and its six alternatives were
quantified in serum samples collected from elder population living around an e-waste …

Effect of bisphenol A on blood glucose, lipid profile and oxidative stress indices in adult male mice

HS Moghaddam, S Samarghandian… - Toxicology …, 2015 - Taylor & Francis
Bisphenol A (BPA), an endocrine-disrupting chemical, has been considered as a possible
risk factor for diabetes and its complications. However, the underlying mechanisms of BPA …

Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2015 - Wiley Online Library
This opinion describes the assessment of the risks to public health associated with
bisphenol A (BPA) exposure. Exposure was assessed for various groups of the human …

Environmental neglect: endocrine disruptors as underappreciated but potentially modifiable diabetes risk factors

RM Sargis, RA Simmons - Diabetologia, 2019 - Springer
Type 2 diabetes prevalence is increasing dramatically across the globe, imposing a
tremendous toll on individuals and healthcare systems. Reversing these trends requires …

Exposure to bisphenol A caused hepatoxicity and intestinal flora disorder in rats

R Liu, B Liu, L Tian, X Jiang, X Li, D Cai, J Sun… - International journal of …, 2022 - mdpi.com
Bisphenol A (BPA) is a globally utilized industrial chemical and is commonly used as a
monomer of polycarbonate plastics and epoxy resins. Recent research reveals that BPA …