[HTML][HTML] Endogenous retroviruses in multiple sclerosis: A network-based etiopathogenic model

S Censi, RM Costantini, A Granzotto… - Ageing Research …, 2024 - Elsevier
The present perspective article proposes an etiopathological model for multiple sclerosis
pathogenesis and progression associated with the activation of human endogenous …

Murine parainfluenza virus persists in lung innate immune cells sustaining chronic lung pathology

ÍA Castro, Y Yang, V Gnazzo, DH Kim… - Nature …, 2024 - nature.com
Common respiratory viruses, including the human parainfluenza viruses, threaten human
health seasonally and associate with the development of chronic lung diseases. Evidence …

A measles virus collective infectious unit that caused lethal human brain disease includes many locally restricted and few widespread copy-back defective genomes

B Taye, I Yousaf, CK Navaratnarajah… - Journal of …, 2024 - journals.asm.org
During virus replication in cultured cells, copy-back defective viral genomes (cbDVGs) can
arise. CbDVGs are powerful inducers of innate immune responses in vitro, but their …

Intra-host genomic diversity and integration landscape of human tissue-resident DNA virome

L Pyöriä, D Pratas, M Toppinen… - Nucleic Acids …, 2024 - academic.oup.com
The viral intra-host genetic diversities and interactions with the human genome during
decades of persistence remain poorly characterized. In this study, we analyzed the …

The measles virus matrix F50S mutation from a lethal case of subacute sclerosing panencephalitis promotes receptor-independent neuronal spread

I Yousaf, L Domanico, T Nambara, K Yadav… - Journal of …, 2025 - journals.asm.org
Subacute sclerosing panencephalitis (SSPE) is a lethal neurological disorder occurring
several years after measles. Reconstruction of the evolution of the measles virus (MeV) …

Reply to Qu et al.,“Quasispecies are constantly selected through virus-encoded intracellular reproductive population bottlenecking”

E Domingo, B Martínez-González… - Journal of …, 2024 - journals.asm.org
J. Han of our minireview on SARS-CoV-2 quasispecies recently published in the Journal of
Virology (1). Qu and colleagues disagree with one of our assertions about viral quasispecies …

Quasispecies productivity

E Domingo, G Witzany - The Science of Nature, 2024 - Springer
The quasispecies theory is a helpful concept in the explanation of RNA virus evolution and
behaviour, with a relevant impact on methods used to fight viral diseases. It has undergone …

High rates of hepatic involvement associated with new epidemic measles strains in Romania

CM Niculae, RM Matoru, O Brîndușe… - Journal of Medical …, 2024 - Wiley Online Library
Similar to other European countries, a measles epidemic dominated by D8 genotype strains
is ongoing since 2022 in our country. Recent reports of liver involvement associated with …

Brain tropism acquisition: the spatial dynamics and evolution of a measles virus collective infectious unit that drove lethal subacute sclerosing panencephalitis

A Hanna - npj Viruses, 2024 - nature.com
Acute viral infections are typically cleared by the host's immune system, but certain RNA
viruses can establish 'within host'persistent infections, for example in the central nervous …

Quasispecies productivity

G Witzany - 2024 - philpapers.org
The quasispecies theory is a helpful concept in the explanation of RNA virus evolution and
behaviour, with a relevant impact on methods used to fight viral diseases. It has undergone …