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Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling
Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …
address defects arising from trauma, inefficient wound repair, or congenital malformation …
Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs
Cellular spheroids are aggregates of cells that are being explored to address fundamental
biological questions and as building blocks for engineered tissues. Spheroids possess …
biological questions and as building blocks for engineered tissues. Spheroids possess …
Injectable MSC spheroid and microgel granular composites for engineering tissue
Many cell types require direct cell–cell interactions for differentiation and function; yet, this
can be challenging to incorporate into 3‐dimensional (3D) structures for the engineering of …
can be challenging to incorporate into 3‐dimensional (3D) structures for the engineering of …
Multisized photoannealable microgels regulate cell spreading, aggregation, and macrophage phenotype through microporous void space
Microgels are an emerging platform for in vitro models and guiding cell fate due to their
inherent porosity and tunability. This work describes a light‐based technique for rapidly …
inherent porosity and tunability. This work describes a light‐based technique for rapidly …
Building a tissue: Mesenchymal and epithelial cell spheroids mechanical properties at micro-and nanoscale
Cell transitions between the epithelial and mesenchymal phenotypes provide the regulated
morphogenesis and regeneration throughout the ontogenesis. The tissue mechanics and …
morphogenesis and regeneration throughout the ontogenesis. The tissue mechanics and …
Label-Free Imaging of Mesenchymal Stem Cell Spheroid Differentiation with Flexible-Probe SECM and a Microfluidic Device
L Zhao, L Wang, J Huang, H Chen, L Liu… - Analytical …, 2024 - ACS Publications
Mesenchymal stem cells (MSCs) have emerged as an indispensable source for stem cell
research and preclinical studies due to their capacity for in vitro proliferation and their …
research and preclinical studies due to their capacity for in vitro proliferation and their …
Microplastic-induced inhibition of cell adhesion and toxicity evaluation using human dermal fibroblast-derived spheroids
S Eom, W Shim, I Choi - Journal of Hazardous Materials, 2024 - Elsevier
Nanoplastics and microplastics (MPs) can significantly affect marine ecosystems and pose
potential risks to human health. Although adverse effects stemming from direct exposure to …
potential risks to human health. Although adverse effects stemming from direct exposure to …
Odontogenesis‐Empowered Extracellular Vesicles Safeguard Donor‐Recipient Stem Cell Interplay to Support Tooth Regeneration
X Huang, B Sui, A Liu, H Guo, C Zheng, P Liu, X Cai… - Small, 2024 - Wiley Online Library
Harnessing the developmental events of mesenchymal condensation to direct postnatal
dental stem cell aggregation represents a cutting‐edge and promising approach to tooth …
dental stem cell aggregation represents a cutting‐edge and promising approach to tooth …
Functionalized Annealed Microgels for Spatial Control of Osteogenic and Chondrogenic Differentiation
The biophysical heterogeneity of the bone–cartilage interface requires complex materials to
mimic differences in bone density, extracellular matrix composition, and mineralization …
mimic differences in bone density, extracellular matrix composition, and mineralization …
[HTML][HTML] Mechanoregulation of MSC spheroid immunomodulation
Mesenchymal stromal cells (MSCs) are widely used in cell-based therapies and tissue
regeneration for their potent secretome, which promotes host cell recruitment and modulates …
regeneration for their potent secretome, which promotes host cell recruitment and modulates …