Lyme disease, or Lyme borreliosis, is the most common tickborne disease in the United
States and Europe. In both locations, Ixodes species ticks transmit the Borrelia burgdorferi …

Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

Infectious agents can trigger autoimmune responses in a number of chronic inflammatory
diseases. Lyme arthritis, which is caused by the tick-transmitted spirochaete Borrelia …

Natural killer (NK) cells and cytotoxic T (CD8+) cells are two of the most important types of
immune cells in our body, protecting it from deadly invaders. While the NK cell is part of the …

Beside mosquitoes, ticks are well-known vectors of different human pathogens. In the
Northern Hemisphere, Lyme borreliosis (Eurasia, LB) or Lyme disease (North America, LD) …

Background: Lyme borreliosis (LB) is the most common tick-borne disease in Europe, but
the burden of disease is incompletely described. Methods: We conducted a systematic …

BACKGROUND Autoimmune diseases often have strong genetic associations with specific
HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked …

Lyme disease is the most common vector-borne disease in North America and Europe. The
clinical manifestations of Lyme disease vary based on the genospecies of the infecting …

Point-of-care serological and direct antigen testing offers actionable insights for diagnosing
challenging illnesses, empowering distributed health systems. Here, we report a POC …

Cardiac involvement is a rare but relevant manifestation of Lyme disease that frequently
presents as atrioventricular block (AVB). Immune-mediated injury has been implicated in the …