In this Series paper, we explore the promises and challenges of artificial intelligence (AI)-
based precision medicine tools in mental health care from clinical, ethical, and regulatory …

Clinical trial results provide the critical evidence base for evaluating the safety and efficacy
of new medicines and medical products. Efficacy and safety may differ among population …

Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …

The year the issues in this report, Improving Representation in Clinical Tri als and Research,
became urgent for me was 2017. I was then chair of the US Preventive Services Task Force …

Despite their premise of objectivity, neuroscience tools for physiological data collection,
such as electroencephalography and functional near-infrared spectroscopy, introduce racial …

Background Patient participation in clinical trials is vital for knowledge advancement and
outcomes improvement. Few adult cancer patients participate in trials. Although patient …

The All of Us Research Program (All of Us) is a national effort to accelerate health research
by exploring the relationship between lifestyle, environment, and genetics. It is set to …

Importance Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD)
clinical trials limits generalizability of results and hinders opportunities to examine potential …

Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled | PLOS Medicine
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Background This study aims to review the literature regarding the barriers to sampling,
recruitment, participation, and retention of members of socioeconomically disadvantaged …