Advancing biosensors with machine learning

F Cui, Y Yue, Y Zhang, Z Zhang, HS Zhou - ACS sensors, 2020 - ACS Publications
Chemometrics play a critical role in biosensors-based detection, analysis, and diagnosis.
Nowadays, as a branch of artificial intelligence (AI), machine learning (ML) have achieved …

Solid-state nanopore platform integrated with machine learning for digital diagnosis of virus infection

A Arima, M Tsutsui, T Washio, Y Baba… - Analytical …, 2020 - ACS Publications
The history of viruses in human society can never be taught without the history of detection
and treatment. As an ancient example, Egyptian mummies have been found to have scars …

A guide to signal processing algorithms for nanopore sensors

C Wen, D Dematties, SL Zhang - ACS sensors, 2021 - ACS Publications
Nanopore technology holds great promise for a wide range of applications such as
biomedical sensing, chemical detection, desalination, and energy conversion. For sensing …

Solid-State Nanopore Distinguishes Ferritin and Apo-Ferritin with Identical Exteriors through Amplified Flexibility at Single-Molecule Level

YD Yin, FF Chen, J Hu, L Yang, XT Song… - Analytical …, 2023 - ACS Publications
Protein identification and discrimination at the single-molecule level are big challenges.
Solid-state nanopores as a sensitive biosensor have been used for protein analysis …

Identifying single viruses using biorecognition solid-state nanopores

A Arima, IH Harlisa, T Yoshida, M Tsutsui… - Journal of the …, 2018 - ACS Publications
Immunosensing is a bioanalytical technique capable of selective detections of pathogens by
utilizing highly specific and strong intermolecular interactions between recognition probes …

Selective detections of single-viruses using solid-state nanopores

A Arima, M Tsutsui, IH Harlisa, T Yoshida, M Tanaka… - Scientific reports, 2018 - nature.com
Rapid diagnosis of flu before symptom onsets can revolutionize our health through
diminishing a risk for serious complication as well as preventing infectious disease outbreak …

All-electrical monitoring of bacterial antibiotic susceptibility in a microfluidic device

Y Yang, K Gupta, KL Ekinci - Proceedings of the National …, 2020 - National Acad Sciences
The lack of rapid antibiotic susceptibility tests adversely affects the treatment of bacterial
infections and contributes to increased prevalence of multidrug-resistant bacteria. Here, we …

Biomimetic nanochannels: From fabrication principles to theoretical insights

X Kan, C Wu, L Wen, L Jiang - Small Methods, 2022 - Wiley Online Library
Biological nanochannels which can regulate ionic transport across cell membranes
intelligently play a significant role in physiological functions. Inspired by these …

Sensing the performance of artificially intelligent nanopores developed by integrating solid-state nanopores with machine learning methods

M Taniguchi, H Takei, K Tomiyasu… - The Journal of …, 2022 - ACS Publications
Solid-state nanopores with a through-hole diameter of less than a few hundred nanometers
can detect single nanoparticles owing to the ionic current flowing through the nanopore …

Protein nanopore-based sensors for public health analyte detection

Y Zhang, C Hu, R Liu, S He, J Yang, W Yao… - Journal of Materials …, 2024 - pubs.rsc.org
High-throughput and label-free protein nanopore-based sensors are extensively used in
DNA sequencing, single-protein analysis, molecular sensing and chemical catalysis with …