Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans

A Grifoni, J Pham, J Sidney, PH O'Rourke… - Journal of …, 2017 - journals.asm.org
While progress has been made in characterizing humoral immunity to Zika virus (ZIKV) in
humans, little is known regarding the corresponding T cell responses to ZIKV. Here, we …

Experimental Zika virus inoculation in a New World monkey model reproduces key features of the human infection

CY Chiu, C Sánchez-San Martín, J Bouquet, T Li… - Scientific Reports, 2017 - nature.com
A monkey model of Zika virus (ZIKV) infection is urgently needed to better understand
transmission and pathogenesis, given its proven association with fetal brain defects in …

Zika virus infection, reproductive organ targeting, and semen transmission in the male olive baboon

J Peregrine, S Gurung, MC Lindgren, S Husain… - Journal of …, 2019 - journals.asm.org
Zika virus (ZIKV) infection in pregnant women is a serious threat to the development and
viability of the fetus. The primary mode of ZIKV transmission to humans is through mosquito …

Recombinant Zika virus subunits are immunogenic and efficacious in mice

A To, LO Medina, KO Mfuh, MM Lieberman, TAS Wong… - MSphere, 2018 - journals.asm.org
Following the 2015 Zika virus (ZIKV) outbreaks in the South Pacific, Caribbean, and
Americas, ZIKV has emerged as a serious threat due to its association with infantile …

Pre-existing T cell memory against Zika virus

B Schouest, A Grifoni, J Pham, J Mateus… - Journal of …, 2021 - journals.asm.org
The mosquito-borne Zika virus (ZIKV) has spread rapidly into regions where dengue virus
(DENV) is endemic, and flavivirus cross-reactive T cell responses have been observed …

Zika virus-immune plasmas from symptomatic and asymptomatic individuals enhance Zika pathogenesis in adult and pregnant mice

BS Shim, YC Kwon, MJ Ricciardi, M Stone, Y Otsuka… - MBio, 2019 - journals.asm.org
Preexisting immunity against dengue virus or West Nile virus was previously reported to
mediate antibody-dependent enhancement (ADE) of Zika virus (ZIKV) infection in a mouse …

Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques

T Singh, IG Miller, S Venkatayogi, H Webster… - MBio, 2024 - journals.asm.org
Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-
reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or …

T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine

R Wang, Z Zhen, L Turtle, B Hou, Y Li, N Wu… - Applied Microbiology …, 2020 - Springer
Zika virus (ZIKV) and Japanese encephalitis virus (JEV) are closely related to mosquito-
borne flaviviruses. Japanese encephalitis (JE) vaccine SA14-14-2 has been in the Chinese …

Replication-deficient zika vector-based vaccine provides maternal and fetal protection in mouse model

G Garcia Jr, N Chakravarty, AE Abu… - Microbiology …, 2022 - journals.asm.org
Zika virus (ZIKV), a mosquito-borne human pathogen, causes dire congenital brain
developmental abnormalities in children of infected mothers. The global health crisis …

Translational model of Zika virus disease in baboons

S Gurung, AN Preno, JP Dubaut, H Nadeau… - Journal of …, 2018 - journals.asm.org
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus with devastating outcomes seen
recently in the Americas due to the association of maternal ZIKV infection with fetal …