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Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans
While progress has been made in characterizing humoral immunity to Zika virus (ZIKV) in
humans, little is known regarding the corresponding T cell responses to ZIKV. Here, we …
humans, little is known regarding the corresponding T cell responses to ZIKV. Here, we …
Experimental Zika virus inoculation in a New World monkey model reproduces key features of the human infection
A monkey model of Zika virus (ZIKV) infection is urgently needed to better understand
transmission and pathogenesis, given its proven association with fetal brain defects in …
transmission and pathogenesis, given its proven association with fetal brain defects in …
Zika virus infection, reproductive organ targeting, and semen transmission in the male olive baboon
J Peregrine, S Gurung, MC Lindgren, S Husain… - Journal of …, 2019 - journals.asm.org
Zika virus (ZIKV) infection in pregnant women is a serious threat to the development and
viability of the fetus. The primary mode of ZIKV transmission to humans is through mosquito …
viability of the fetus. The primary mode of ZIKV transmission to humans is through mosquito …
Recombinant Zika virus subunits are immunogenic and efficacious in mice
A To, LO Medina, KO Mfuh, MM Lieberman, TAS Wong… - MSphere, 2018 - journals.asm.org
Following the 2015 Zika virus (ZIKV) outbreaks in the South Pacific, Caribbean, and
Americas, ZIKV has emerged as a serious threat due to its association with infantile …
Americas, ZIKV has emerged as a serious threat due to its association with infantile …
Pre-existing T cell memory against Zika virus
The mosquito-borne Zika virus (ZIKV) has spread rapidly into regions where dengue virus
(DENV) is endemic, and flavivirus cross-reactive T cell responses have been observed …
(DENV) is endemic, and flavivirus cross-reactive T cell responses have been observed …
Zika virus-immune plasmas from symptomatic and asymptomatic individuals enhance Zika pathogenesis in adult and pregnant mice
Preexisting immunity against dengue virus or West Nile virus was previously reported to
mediate antibody-dependent enhancement (ADE) of Zika virus (ZIKV) infection in a mouse …
mediate antibody-dependent enhancement (ADE) of Zika virus (ZIKV) infection in a mouse …
Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques
T Singh, IG Miller, S Venkatayogi, H Webster… - MBio, 2024 - journals.asm.org
Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-
reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or …
reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or …
T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine
Zika virus (ZIKV) and Japanese encephalitis virus (JEV) are closely related to mosquito-
borne flaviviruses. Japanese encephalitis (JE) vaccine SA14-14-2 has been in the Chinese …
borne flaviviruses. Japanese encephalitis (JE) vaccine SA14-14-2 has been in the Chinese …
Replication-deficient zika vector-based vaccine provides maternal and fetal protection in mouse model
G Garcia Jr, N Chakravarty, AE Abu… - Microbiology …, 2022 - journals.asm.org
Zika virus (ZIKV), a mosquito-borne human pathogen, causes dire congenital brain
developmental abnormalities in children of infected mothers. The global health crisis …
developmental abnormalities in children of infected mothers. The global health crisis …
Translational model of Zika virus disease in baboons
S Gurung, AN Preno, JP Dubaut, H Nadeau… - Journal of …, 2018 - journals.asm.org
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus with devastating outcomes seen
recently in the Americas due to the association of maternal ZIKV infection with fetal …
recently in the Americas due to the association of maternal ZIKV infection with fetal …