The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction
Dystrophin is the central protein of the dystrophin-glycoprotein complex (DGC) in skeletal
and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix …
and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix …
Evolution and developmental functions of the dystrophin-associated protein complex: Beyond the idea of a muscle-specific cell adhesion complex
V Mirouse - Frontiers in cell and developmental biology, 2023 - frontiersin.org
The Dystrophin-Associated Protein Complex (DAPC) is a well-defined and evolutionarily
conserved complex in animals. DAPC interacts with the F-actin cytoskeleton via dystrophin …
conserved complex in animals. DAPC interacts with the F-actin cytoskeleton via dystrophin …
RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes
Mechanical forces drive critical cellular processes that are reflected in mechanical
phenotypes, or mechanotypes, of cells and their microenvironment. We present here …
phenotypes, or mechanotypes, of cells and their microenvironment. We present here …
Duchenne muscular dystrophy treatment with lentiviral vector containing mini‐dystrophin gene in vivo
X Wang, Y Zhu, T Liu, L Zhou, Y Fu, J Zhao, Y Li… - MedComm, 2024 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is an incurable X‐linked recessive genetic disease
caused by mutations in the dystrophin gene. Many researchers aim to restore truncated …
caused by mutations in the dystrophin gene. Many researchers aim to restore truncated …
Systemic treatment of body‐wide Duchenne muscular dystrophy symptoms
P Konieczny - Clinical Pharmacology & Therapeutics, 2024 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease that leads to premature
death due to the loss of dystrophin. Current strategies predominantly focus on the …
death due to the loss of dystrophin. Current strategies predominantly focus on the …
Dystrophin-and utrophin-based therapeutic approaches for treatment of duchenne muscular dystrophy: a comparative review
Duchenne muscular dystrophy is a devastating disease that leads to progressive muscle
loss and premature death. While medical management focuses mostly on symptomatic …
loss and premature death. While medical management focuses mostly on symptomatic …
[HTML][HTML] Analysis of common and characteristic actions of Panax ginseng and Panax notoginseng in wound healing based on network pharmacology and meta …
Z Wang, X **e, M Wang, M Ding, S Gu, X **ng… - Journal of Ginseng …, 2023 - Elsevier
In recent years, an increasing number of reports have explored the wound healing
mechanism of these two traditional Chinese herbal medicines-Panax ginseng and Panax …
mechanism of these two traditional Chinese herbal medicines-Panax ginseng and Panax …
Ablation of the dystrophin Dp71f alternative C-terminal variant increases sarcoma tumour cell aggressiveness
Alterations in Dp71 expression, the most ubiquitous dystrophin isoform, have been
associated with patient survival across tumours. Intriguingly, in certain malignancies, Dp71 …
associated with patient survival across tumours. Intriguingly, in certain malignancies, Dp71 …
Chiral Cell Nanomechanics Originated in Clockwise/Counterclockwise Biofunctional Microarrays to Govern the Nuclear Mechanotransduction of Mesenchymal Stem …
Cell chirality is extremely important for the evolution of cell morphogenesis to manipulate
cell performance due to left–right asymmetry. Although chiral micro-and nanoscale …
cell performance due to left–right asymmetry. Although chiral micro-and nanoscale …
[HTML][HTML] The unconditioned fear response in vertebrates deficient in dystrophin
S Gharibi, C Vaillend, A Lindsay - Progress in Neurobiology, 2024 - Elsevier
Dystrophin loss due to mutations in the Duchenne muscular dystrophy (DMD) gene is
associated with a wide spectrum of neurocognitive comorbidities, including an aberrant …
associated with a wide spectrum of neurocognitive comorbidities, including an aberrant …