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Growth and division of the peptidoglycan matrix
PDA Rohs, TG Bernhardt - Annual review of microbiology, 2021 - annualreviews.org
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
Recent advances of utilizing artificial intelligence in lab on a chip for diagnosis and treatment
Nowadays, artificial intelligence (AI) creates numerous promising opportunities in the life
sciences. AI methods can be significantly advantageous for analyzing the massive datasets …
sciences. AI methods can be significantly advantageous for analyzing the massive datasets …
Peptidoglycan: structure, synthesis, and regulation
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality
Bactericidal antibiotics kill bacteria by perturbing various cellular targets and processes.
Disruption of the primary antibiotic-binding partner induces a cascade of molecular events …
Disruption of the primary antibiotic-binding partner induces a cascade of molecular events …
How to build a bacterial cell: MreB as the foreman of E. coli construction
Cell shape matters across the kingdoms of life, and cells have the remarkable capacity to
define and maintain specific shapes and sizes. But how are the shapes of micron-sized cells …
define and maintain specific shapes and sizes. But how are the shapes of micron-sized cells …
Homeostasis of protein and mRNA concentrations in growing cells
Many experiments show that the numbers of mRNA and protein are proportional to the cell
volume in growing cells. However, models of stochastic gene expression often assume …
volume in growing cells. However, models of stochastic gene expression often assume …
Subcellular organization: a critical feature of bacterial cell replication
Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of
cellular life, display defined shapes and complex internal organization, showcasing a highly …
cellular life, display defined shapes and complex internal organization, showcasing a highly …
Regulation of microbial growth by turgor pressure
Highlights•Recent studies have revealed various ways that turgor regulates microbial
growth.•In Gram-positive rods, membrane tension transiently inhibits wall growth via …
growth.•In Gram-positive rods, membrane tension transiently inhibits wall growth via …
Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects
Cell shape and cell-envelope integrity of bacteria are determined by the peptidoglycan cell
wall. In rod-shaped Escherichia coli, two conserved sets of machinery are essential for cell …
wall. In rod-shaped Escherichia coli, two conserved sets of machinery are essential for cell …
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery
Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved
morphogenic complex that spatially controls cell wall assembly by the glycan polymerase …
morphogenic complex that spatially controls cell wall assembly by the glycan polymerase …