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Exploration of computational aids for effective drug designing and management of viral diseases: A comprehensive review
T Khan, S Raza - Current Topics in Medicinal Chemistry, 2023 - benthamdirect.com
Background: Microbial diseases, specifically originating from viruses are the major cause of
human mortality all over the world. The current COVID-19 pandemic is a case in point …
human mortality all over the world. The current COVID-19 pandemic is a case in point …
Review of computational methods for virus–host protein interaction prediction: a case study on novel Ebola–human interactions
Identification of potential virus–host interactions is useful and vital to control the highly
infectious virus-caused diseases. This may contribute toward development of new drugs to …
infectious virus-caused diseases. This may contribute toward development of new drugs to …
Genome-wide identification and expression analysis of wall-associated kinase (WAK) gene family in potato (Solanum tuberosum L.)
H Yu, W Zhang, Y Kang, Y Fan, X Yang, M Shi… - Plant Biotechnology …, 2022 - Springer
The wall-associated kinases (WAKs) and wall-associated kinase like (WAKL) play a vital
regulating role in responses to diverse environment stresses and pathogenic microbes in …
regulating role in responses to diverse environment stresses and pathogenic microbes in …
Wall associated kinases (WAKs) gene family in tomato (Solanum lycopersicum): insights into plant immunity
Abstract Wall-associated kinases (WAKs), a subgroup of receptor-like kinases (RLKs), are
localized on the cell wall and have roles in pathogen recognition and signal transduction in …
localized on the cell wall and have roles in pathogen recognition and signal transduction in …
Composite structural motifs of binding sites for delineating biological functions of proteins
AR Kinjo, H Nakamura - PloS one, 2012 - journals.plos.org
Most biological processes are described as a series of interactions between proteins and
other molecules, and interactions are in turn described in terms of atomic structures. To …
other molecules, and interactions are in turn described in terms of atomic structures. To …
Fast protein binding site comparisons using visual words representation
Motivation: Finding geometrically similar protein binding sites is crucial for understanding
protein functions and can provide valuable information for protein–protein docking and drug …
protein functions and can provide valuable information for protein–protein docking and drug …
Sequence and structure properties uncover the natural classification of protein complexes formed by intrinsically disordered proteins via mutual synergistic folding
Intrinsically disordered proteins mediate crucial biological functions through their
interactions with other proteins. Mutual synergistic folding (MSF) occurs when all interacting …
interactions with other proteins. Mutual synergistic folding (MSF) occurs when all interacting …
PBSword: a web server for searching similar protein–protein binding sites
PBSword is a web server designed for efficient and accurate comparisons and searches of
geometrically similar protein–protein binding sites from a large-scale database. The basic …
geometrically similar protein–protein binding sites from a large-scale database. The basic …
Drug Discovery by Targeting Protein–Protein Interactions
L Bettinetti, M Magnani, A Padova - … of Protein-Protein Interfaces: In Search …, 2013 - Springer
For many years, drug discovery's main interest has focused on protein–ligand interactions,
such as enzyme inhibition or transmembrane receptor modulation. Drug discovery …
such as enzyme inhibition or transmembrane receptor modulation. Drug discovery …