Exploration of computational aids for effective drug designing and management of viral diseases: A comprehensive review

T Khan, S Raza - Current Topics in Medicinal Chemistry, 2023 - benthamdirect.com
Background: Microbial diseases, specifically originating from viruses are the major cause of
human mortality all over the world. The current COVID-19 pandemic is a case in point …

Review of computational methods for virus–host protein interaction prediction: a case study on novel Ebola–human interactions

AK Halder, P Dutta, M Kundu, S Basu… - Briefings in functional …, 2018 - academic.oup.com
Identification of potential virus–host interactions is useful and vital to control the highly
infectious virus-caused diseases. This may contribute toward development of new drugs to …

Genome-wide identification and expression analysis of wall-associated kinase (WAK) gene family in potato (Solanum tuberosum L.)

H Yu, W Zhang, Y Kang, Y Fan, X Yang, M Shi… - Plant Biotechnology …, 2022 - Springer
The wall-associated kinases (WAKs) and wall-associated kinase like (WAKL) play a vital
regulating role in responses to diverse environment stresses and pathogenic microbes in …

Wall associated kinases (WAKs) gene family in tomato (Solanum lycopersicum): insights into plant immunity

F Kurt, B Kurt, E Filiz - Gene Reports, 2020 - Elsevier
Abstract Wall-associated kinases (WAKs), a subgroup of receptor-like kinases (RLKs), are
localized on the cell wall and have roles in pathogen recognition and signal transduction in …

Composite structural motifs of binding sites for delineating biological functions of proteins

AR Kinjo, H Nakamura - PloS one, 2012 - journals.plos.org
Most biological processes are described as a series of interactions between proteins and
other molecules, and interactions are in turn described in terms of atomic structures. To …

Fast protein binding site comparisons using visual words representation

B Pang, N Zhao, D Korkin, CR Shyu - Bioinformatics, 2012 - academic.oup.com
Motivation: Finding geometrically similar protein binding sites is crucial for understanding
protein functions and can provide valuable information for protein–protein docking and drug …

Sequence and structure properties uncover the natural classification of protein complexes formed by intrinsically disordered proteins via mutual synergistic folding

B Mészáros, L Dobson, E Fichó, I Simon - International Journal of …, 2019 - mdpi.com
Intrinsically disordered proteins mediate crucial biological functions through their
interactions with other proteins. Mutual synergistic folding (MSF) occurs when all interacting …

PBSword: a web server for searching similar protein–protein binding sites

B Pang, X Kuang, N Zhao, D Korkin… - Nucleic acids …, 2012 - academic.oup.com
PBSword is a web server designed for efficient and accurate comparisons and searches of
geometrically similar protein–protein binding sites from a large-scale database. The basic …

Drug Discovery by Targeting Protein–Protein Interactions

L Bettinetti, M Magnani, A Padova - … of Protein-Protein Interfaces: In Search …, 2013 - Springer
For many years, drug discovery's main interest has focused on protein–ligand interactions,
such as enzyme inhibition or transmembrane receptor modulation. Drug discovery …