Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Background: This document provides evidence-based clinical practice guidelines on the
management of adult patients with community-acquired pneumonia. Methods: A …

Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …

Severe or life threatening infections are common among patients in the intensive care unit
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Background Antimicrobial de-escalation (ADE) is a strategy of antimicrobial stewardship,
aiming at preventing the emergence of antimicrobial resistance (AMR) by decreasing the …