According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast
number of biological processes through intercellular transfer of biomolecules. Increasing …

Emerging evidence suggests that host glycans influence severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain …

The heterogeneity of exosomal populations has hindered our understanding of their
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …

Great advances have been made in mass spectrometric data interpretation for intact
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …

The dense O-glycosylation of mucins plays an important role in the defensive properties of
the mucus hydrogel. Aberrant glycosylation is often correlated with inflammation and …

The glycosylation on the spike (S) protein of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, modulates the viral infection …

Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins
and lipids, are arguably the most abundant and structurally diverse class of molecules in …

Glycans constitute the most complicated post-translational modification, modulating protein
activity in health and disease. However, structural annotation from tandem mass …

Despite the fundamental roles of sialyl-and fucosyltransferases in mammalian physiology,
there are few pharmacological tools to manipulate their function in a cellular setting …