Zebrafish as a model organism for neurodegenerative disease

K Chia, A Klingseisen, D Sieger… - Frontiers in molecular …, 2022 - frontiersin.org
The zebrafish is increasingly recognized as a model organism for translational research into
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …

Advances of zebrafish in neurodegenerative disease: from models to drug discovery

X Wang, JB Zhang, KJ He, F Wang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …

Evaluation of models of Parkinson's disease

SA Jagmag, N Tripathi, SD Shukla, S Maiti… - Frontiers in …, 2016 - frontiersin.org
Parkinson's disease is one of the most common neurodegenerative diseases. Animal
models have contributed a large part to our understanding and therapeutics developed for …

Zebrafish as an animal model for drug discovery in Parkinson's disease and other movement disorders: a systematic review

RL Vaz, TF Outeiro, JJ Ferreira - Frontiers in neurology, 2018 - frontiersin.org
Movement disorders can be primarily divided into hypokinetic and hyperkinetic. Most of the
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …

[HTML][HTML] Effect of dietary selenium on the growth and immune systems of fish

SL Sumana, H Chen, Y Shui, C Zhang, F Yu, J Zhu… - Animals, 2023 - mdpi.com
Simple Summary This paper addresses the various sources of Se in the aquatic
environment as well as the positive and negative effects on fish. It emphasizes that optimal …

Modeling neurodegenerative disorders in zebrafish

AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model

AD Zharikov, JR Cannon, V Tapias, Q Bai… - The Journal of clinical …, 2015 - jci.org
Multiple convergent lines of evidence implicate both α-synuclein (encoded by SCNA) and
mitochondrial dysfunction in the pathogenesis of sporadic Parkinson's disease (PD) …

A critical review of zebrafish models of Parkinson's disease

JM Doyle, RP Croll - Frontiers in Pharmacology, 2022 - frontiersin.org
A wide variety of human diseases have been modelled in zebrafish, including various types
of cancer, cardiovascular diseases and neurodegenerative diseases like Alzheimer's and …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …