Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

HH Han, HM Wang, P Jangili, M Li, L Wu… - Chemical Society …, 2023 - pubs.rsc.org
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Research advances in BODIPY-assembled supramolecular photosensitizers for photodynamic therapy

J Wang, Q Gong, L Jiao, E Hao - Coordination Chemistry Reviews, 2023 - Elsevier
Photodynamic therapy (PDT) is a promising therapeutic approach for anticancer and
antibacterial treatment via photoinduced reactive oxygen species (ROS) generation …

Photocatalytic superoxide radical generator that induces pyroptosis in cancer cells

L Yu, Y Xu, Z Pu, H Kang, M Li… - Journal of the …, 2022 - ACS Publications
Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …

Photon-controlled pyroptosis activation (photopyro): an emerging trigger for antitumor immune response

M Li, J Kim, H Rha, S Son, MS Levine… - Journal of the …, 2023 - ACS Publications
Pyroptosis refers to the process of gasdermin-mediated lytic programmed cell death (PCD)
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

X Zhao, J Liu, J Fan, H Chao, X Peng - Chemical Society Reviews, 2021 - pubs.rsc.org
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Recent advances and prospects in organic molecule-based phototheranostic agents for enhanced cancer phototherapy

YY Zhao, H Kim, VN Nguyen, S Jang, WJ Jang… - Coordination Chemistry …, 2024 - Elsevier
Phototherapy, includes photodynamic therapy (PDT) and photothermal therapy (PTT), which
combine light with an adequate wavelength and a chemical phototheranostic agent in the …

From Low to No O2-Dependent Hypoxia Photodynamic Therapy (hPDT): A New Perspective

M Li, Y Xu, X Peng, JS Kim - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus The advent of photochemical techniques has revolutionized the landscape of
biology and medical sciences. Especially appealing in this context is photodynamic therapy …