Molecular imaging in drug discovery and development
Imaging sciences have grown exponentially during the past three decades, and many
techniques, such as magnetic resonance imaging, nuclear tomographic imaging and X-ray …
techniques, such as magnetic resonance imaging, nuclear tomographic imaging and X-ray …
Magnetic resonance imaging in experimental models of brain disorders
This review gives an overview of the application of magnetic resonance imaging (MRI) in
experimental models of brain disorders. MRI is a noninvasive and versatile imaging modality …
experimental models of brain disorders. MRI is a noninvasive and versatile imaging modality …
Three-dimensional cerebral vasculature of the CBA mouse brain: a magnetic resonance imaging and micro computed tomography study
Studies of mouse cerebral vasculature to date have focused on the circle of Willis without
examining the morphological distribution of blood vessels through the rest of the brain …
examining the morphological distribution of blood vessels through the rest of the brain …
Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia—an ultrasound and MRI study
MH Wilson, MEG Edsell… - Journal of Cerebral …, 2011 - journals.sagepub.com
Transcranial Doppler is a widely used noninvasive technique for assessing cerebral artery
blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field …
blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field …
4D microvascular imaging based on ultrafast Doppler tomography
Abstract 4D ultrasound microvascular imaging was demonstrated by applying ultrafast
Doppler tomography (UFD-T) to the imaging of brain hemodynamics in rodents. In vivo real …
Doppler tomography (UFD-T) to the imaging of brain hemodynamics in rodents. In vivo real …
Age-dependent cerebrovascular abnormalities and blood flow disturbances in APP23 mice modeling Alzheimer's disease
N Beckmann, A Schuler, T Mueggler… - Journal of …, 2003 - jneurosci.org
Neuropathological changes associated with Alzheimer9s disease (AD) such as
amyloidplaques, cerebral amyloid angiopathy, and related pathologies are reproduced in …
amyloidplaques, cerebral amyloid angiopathy, and related pathologies are reproduced in …
Imaging of cerebrovascular pathology in animal models of Alzheimer's disease
In Alzheimer's disease (AD), vascular pathology may interact with neurodegeneration and
thus aggravate cognitive decline. As the relationship between these two processes is poorly …
thus aggravate cognitive decline. As the relationship between these two processes is poorly …
Complications and pitfalls in rat stroke models for middle cerebral artery occlusion: a comparison between the suture and the macrosphere model using magnetic …
T Gerriets, E Stolz, M Walberer, C Muller, C Rottger… - Stroke, 2004 - ahajournals.org
Background and Purpose—Investigating focal cerebral ischemia requires animal models
that are relevant to human stroke. Complications and side effects are common among these …
that are relevant to human stroke. Complications and side effects are common among these …
High resolution magnetic resonance angiography non‐invasively reveals mouse strain differences in the cerebrovascular anatomy in vivo
N Beckmann - Magnetic Resonance in Medicine: An Official …, 2000 - Wiley Online Library
High resolution magnetic resonance angiography (MRA) revealed highly variable arterial
cerebrovascular structures in mice from different strains and within the same strain …
cerebrovascular structures in mice from different strains and within the same strain …
Contrast-enhanced magnetic resonance microangiography reveals remodeling of the cerebral microvasculature in transgenic ArcAβ mice
J Klohs, C Baltes, F Princz-Kranz, D Ratering… - Journal of …, 2012 - jneurosci.org
Amyloid-β (Aβ) deposition in the cerebral vasculature is accompanied by remodeling which
has a profound influence on vascular integrity and function. In the current study we have …
has a profound influence on vascular integrity and function. In the current study we have …