Anatomy and physiology of the urinary tract: relation to host defense and microbial infection

DR Hickling, TT Sun, XR Wu - Urinary tract infections …, 2017 - Wiley Online Library
The mammalian urinary tract is a contiguous hollow‐organ system whose primary function is
to collect, transport, store, and expel urine periodically and in a highly coordinated fashion …

Opinion: what is the normal prevalence of vesicoureteral reflux?

MA Sargent - Pediatric radiology, 2000 - Springer
Background. The prevalence of vesicoureteral reflux in normal children has been estimated
to be 0.4% to 1.8%. Based on epidemiological data, it can be estimated that 2.2% of girls …

Clinical practice guideline on pregnancy and renal disease

K Wiles, L Chappell, K Clark, L Elman, M Hall… - BMC nephrology, 2019 - Springer
Background Chronic kidney disease (CKD) is estimated to affect 3% of pregnant women in
high-income countries,(Piccoli et al., 2018,# 13860) which equates to between 15,000 …

The Swedish reflux trial in children: III. Urinary tract infection pattern

P Brandström, E Esbjörner, M Herthelius… - The Journal of …, 2010 - auajournals.org
Purpose: We evaluated the difference in the febrile urinary tract infection rate in small
children with dilating vesicoureteral reflux randomly allocated to 3 management alternatives …

Reproductive health and pregnancy in women with chronic kidney disease

KS Wiles, C Nelson-Piercy, K Bramham - Nature Reviews Nephrology, 2018 - nature.com
Chronic kidney disease (CKD) is associated with reduced fertility and an increased risk of
adverse pregnancy outcomes. Rates of pre-eclampsia, fetal growth restriction and preterm …

Vesicoureteral reflux

G Williams, JT Fletcher, SI Alexander… - Journal of the American …, 2008 - journals.lww.com
Vesicoureteral reflux (VUR), the retrograde flow of urine from the bladder toward the kidney,
is common in young children. About 30% of children with urinary tract infections will be …

Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux

P Hu, FM Deng, FX Liang, CM Hu… - The Journal of cell …, 2000 - rupress.org
Urothelium synthesizes a group of integral membrane proteins called uroplakins, which form
two-dimensional crystals (urothelial plaques) covering> 90% of the apical urothelial surface …

Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux

W Lu, AM Van Eerde, X Fan, F Quintero-Rivera… - The American Journal of …, 2007 - cell.com
Congenital anomalies of the kidney and urinary tract (CAKUT) include vesicoureteral reflux
(VUR). VUR is a complex, genetically heterogeneous developmental disorder characterized …

Vesico‐ureteric reflux: occurrence and long‐term risks

SH Jacobson, S Hansson, B Jakobsson - Acta paediatrica, 1999 - Wiley Online Library
The prevalence of vesico‐ureteric reflux in the general population is unknown, but it is
increased in risk groups, such as children with symptomatic urinary tract infection …

Primary vesicoureteral reflux and renal scarring

TK Mattoo, D Mohammad - Pediatric Clinics, 2022 - pediatric.theclinics.com
Vesicoureteral reflux (VUR) may be primary or secondary. Primary VUR is the most common
congenital anomaly of urinary tract that is diagnosed mostly after urinary tract infection (UTI) …