Since the first derivation of human pluripotent stem cells (hPSCs) 27 years ago,
technologies to control their differentiation and manufacturing have advanced immensely …

Inherited retinal degeneration (IRD) disease and age-related macular degeneration (AMD)
are leading causes of irreversible vision loss and blindness. Although significant progress …

Retinal degenerative diseases are a major cause of blindness involving the dysfunction of
photoreceptors, retinal pigmented epithelium (RPE), or both. A promising treatment …

The transplantation of human organoid-derived retinal cells is being studied as a potentially
viable strategy to treat vision loss due to retinal degeneration. Experiments in animal models …

Age-related macular degeneration (AMD) is a leading cause of blindness, and elucidating
its underlying disease mechanisms is vital to the development of appropriate therapeutics …

Ion channels in retinal pigment epithelial (RPE) cells are crucial for retinal health and vision
functions. Defects in such channels are intricately associated with the development of …

Nanotechnology has demonstrated tremendous promise in the realm of ocular illnesses,
with applications for disease detection and therapeutic interventions. The nanoscale …

Background Age-related macular degeneration (AMD) is a prevalent ocular pathology
affecting mostly the elderly population. AMD is characterized by a progressive retinal …

Background aims With the continuous development and advancement of human pluripotent
stem cell (PSC)-derived cell therapies, an ever-increasing number of clinical indications can …

Age-related macular degeneration (AMD) is one of the leading causes of visual loss in older
patients. No effective drug is available for this pathology, but studies about therapy with stem …