Biphasic Dynamics of Macrophage Immunometabolism during Mycobacterium tuberculosis Infection
Macrophages are the primary targets of Mycobacterium tuberculosis infection; the early
events of macrophage interaction with M. tuberculosis define subsequent progression and …
events of macrophage interaction with M. tuberculosis define subsequent progression and …
Progress of stimulus responsive nanosystems for targeting treatment of bacterial infectious diseases
N Yang, M Sun, H Wang, D Hu, A Zhang, S Khan… - Advances in Colloid and …, 2024 - Elsevier
In recent decades, due to insufficient concentration at the lesion site, low bioavailability and
increasingly serious resistance, antibiotics have become less and less dominant in the …
increasingly serious resistance, antibiotics have become less and less dominant in the …
Host-mediated ubiquitination of a mycobacterial protein suppresses immunity
L Wang, J Wu, J Li, H Yang, T Tang, H Liang, M Zuo… - Nature, 2020 - nature.com
Mycobacterium tuberculosis is an intracellular pathogen that uses several strategies to
interfere with the signalling functions of host immune molecules. Many other bacterial …
interfere with the signalling functions of host immune molecules. Many other bacterial …
Glutamine is required for M1-like polarization of macrophages in response to Mycobacterium tuberculosis infection
In response to Mycobacterium tuberculosis infection, macrophages mount proinflammatory
and antimicrobial responses similar to those observed in M1 macrophages activated by …
and antimicrobial responses similar to those observed in M1 macrophages activated by …
The advances in adjuvant therapy for tuberculosis with immunoregulatory compounds
J Mi, X Wu, J Liang - Frontiers in Microbiology, 2024 - frontiersin.org
Tuberculosis (TB) is a chronic bacterial disease, as well as a complex immune disease. The
occurrence, development, and prognosis of TB are not only related to the pathogenicity of …
occurrence, development, and prognosis of TB are not only related to the pathogenicity of …
Immunometabolism during Mycobacterium tuberculosis infection
NC Howard, SA Khader - Trends in microbiology, 2020 - cell.com
Over a quarter of the world's population is infected with Mycobacterium tuberculosis (Mtb),
the causative agent of tuberculosis (TB). Approximately 3.4% of new and 18% of recurrent …
the causative agent of tuberculosis (TB). Approximately 3.4% of new and 18% of recurrent …
[PDF][PDF] Ferroptosis in neurodegenerative diseases: inhibitors as promising candidate mitigators.
RF Zhang, M Zeng, N Lv, LM Wang… - European Review for …, 2023 - europeanreview.org
Ferroptosis is a new form of iron-dependent programmed cell death, characterized by
intracellular iron overload and lipid peroxidation. Several studies have revealed that …
intracellular iron overload and lipid peroxidation. Several studies have revealed that …
Ibrutinib suppresses intracellular mycobacterium tuberculosis growth by inducing macrophage autophagy
Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. The host-directed
therapy is a promising strategy for TB treatment that synergize with anti-TB treatment drugs …
therapy is a promising strategy for TB treatment that synergize with anti-TB treatment drugs …
Chemistry and redox biology of mycothiol
Abstract Significance: Mycothiol (MSH, AcCys-GlcN-Ins) is the main low-molecular weight
(LMW) thiol of most Actinomycetes, including the human pathogen Mycobacterium …
(LMW) thiol of most Actinomycetes, including the human pathogen Mycobacterium …
Role of Sirt1 in innate immune mechanisms against Mycobacterium tuberculosis via the inhibition of TAK1 activation
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) has an alarming mortality
rate, and the fast-growing drug resistance of Mtb necessitates the discovery and application …
rate, and the fast-growing drug resistance of Mtb necessitates the discovery and application …