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Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
Gastrointestinal biofilms in health and disease
Microorganisms colonize various ecological niches in the human habitat, as they do in
nature. Predominant forms of multicellular communities called biofilms colonize human …
nature. Predominant forms of multicellular communities called biofilms colonize human …
Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
Defining the complex role of the microbiome in colorectal cancer and the discovery of novel,
protumorigenic microbes are areas of active investigation. In the present study, culturing and …
protumorigenic microbes are areas of active investigation. In the present study, culturing and …
Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 …
C Kong, X Yan, Y Zhu, H Zhu, Y Luo, P Liu… - Cancer …, 2021 - aacrjournals.org
Emerging research has revealed regulation of colorectal cancer metabolism by bacteria.
Fusobacterium nucleatum (Fn) plays a crucial role in the development of colorectal cancer …
Fusobacterium nucleatum (Fn) plays a crucial role in the development of colorectal cancer …
[HTML][HTML] Host/microbiota interactions in health and diseases—Time for mucosal microbiology!
During the last 20 years, a new field of research delineating the importance of the microbiota
in health and diseases has emerged. Inappropriate host-microbiota interactions have been …
in health and diseases has emerged. Inappropriate host-microbiota interactions have been …
Fecal let-7b and miR-21 directly modulate the intestinal microbiota, driving chronic inflammation
M Casado-Bedmar, M Roy, L Berthet, JP Hugot… - Gut …, 2024 - Taylor & Francis
Inflammatory bowel diseases (IBD) etiology is multifactorial. Luminal microRNAs (miRNAs)
have been suspected to play a role in the promotion of chronic inflammation, but the extent …
have been suspected to play a role in the promotion of chronic inflammation, but the extent …
MicroRNA and gut microbiota: tiny but mighty—novel insights into their cross-talk in inflammatory bowel disease pathogenesis and therapeutics
M Casado-Bedmar, E Viennois - Journal of Crohn's and Colitis, 2022 - academic.oup.com
Abstract MicroRNAs [miRNAs], small non-coding RNAs, have recently been described as
crucial contributors to intestinal homeostasis. They can interact with the gut microbiota in a …
crucial contributors to intestinal homeostasis. They can interact with the gut microbiota in a …
TP53 Gain-of-Function and Non–Gain-of-Function Mutations Are Differentially Associated With Sidedness-Dependent Prognosis in Metastatic Colorectal Cancer
M Pan, C Jiang, P Tse, N Achacoso… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To examine the association of gain-of-function (GOF) and non–gain-of-function
(non-GOF) TP53 mutations with prognosis of metastatic right-sided (RCC) versus left-sided …
(non-GOF) TP53 mutations with prognosis of metastatic right-sided (RCC) versus left-sided …
[HTML][HTML] MicroRNAs regulate intestinal immunity and gut microbiota for gastrointestinal health: A comprehensive review
K Bi, X Zhang, W Chen, H Diao - Genes, 2020 - mdpi.com
MicroRNAs are small non-coding RNAs regulating gene expression at the post-
transcriptional level. The regulation of microRNA expression in the gut intestine is gradually …
transcriptional level. The regulation of microRNA expression in the gut intestine is gradually …
Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities
The human intestinal tract harbors a profound variety of microorganisms that live in
symbiosis with the host and each other. It is a complex and highly dynamic environment …
symbiosis with the host and each other. It is a complex and highly dynamic environment …