The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis
The nucleus accumbens is a major input structure of the basal ganglia and integrates
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …
Magnetically enhanced nucleic acid delivery. Ten years of magnetofection—Progress and prospects
C Plank, O Zelphati, O Mykhaylyk - Advanced drug delivery reviews, 2011 - Elsevier
Nucleic acids carry the building plans of living systems. As such, they can be exploited to
make cells produce a desired protein, or to shut down the expression of endogenous genes …
make cells produce a desired protein, or to shut down the expression of endogenous genes …
Integrin-linked kinase–essential roles in physiology and cancer biology
PC McDonald, AB Fielding… - Journal of cell …, 2008 - journals.biologists.com
Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions
and regulates many cellular processes, including growth, proliferation, survival …
and regulates many cellular processes, including growth, proliferation, survival …
The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!
SA Wickström, A Lange, E Montanez, R Fässler - The EMBO journal, 2010 - embopress.org
Dynamic interactions of cells with their environment regulate multiple aspects of tissue
morphogenesis and function. Integrins are the major class of cell surface receptors that …
morphogenesis and function. Integrins are the major class of cell surface receptors that …
Integrin-linked kinase (ILK): the known vs. the unknown and perspectives
A Górska, AJ Mazur - Cellular and Molecular Life Sciences, 2022 - Springer
Integrin-linked kinase (ILK) is a multifunctional molecular actor in cell–matrix interactions,
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …
Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3
X Chai, E Förster, S Zhao, HH Bock… - Journal of …, 2009 - Soc Neuroscience
The extracellular matrix protein Reelin, secreted by Cajal-Retzius cells in the marginal zone
of the cortex, controls the radial migration of cortical neurons. Reelin signaling involves the …
of the cortex, controls the radial migration of cortical neurons. Reelin signaling involves the …
Triggering biological processes: methods and applications of photocaged peptides and proteins
AE Mangubat-Medina, ZT Ball - Chemical Society Reviews, 2021 - pubs.rsc.org
There has been a significant push in recent years to deploy fundamental knowledge and
methods of photochemistry toward biological ends. Photoreactive groups have enabled …
methods of photochemistry toward biological ends. Photoreactive groups have enabled …
The sarcomeric Z‐disc and Z‐discopathies
R Knöll, B Buyandelger, M Lab - BioMed Research …, 2011 - Wiley Online Library
The sarcomeric Z‐disc defines the lateral borders of the sarcomere and has primarily been
seen as a structure important for mechanical stability. This view has changed dramatically …
seen as a structure important for mechanical stability. This view has changed dramatically …
Understanding the molecular basis of cardiomyopathy
Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can
be caused by mutations in a wide range of proteins located in different cellular …
be caused by mutations in a wide range of proteins located in different cellular …
The tetrapartite synapse: extracellular matrix remodeling contributes to corticoaccumbens plasticity underlying drug addiction
Synaptic plasticity has long been known to involve three key elements of neuropil, the
presynapse, the postsynapse and adjacent glia. Here we review the role of the extracellular …
presynapse, the postsynapse and adjacent glia. Here we review the role of the extracellular …