Hierarchical orders are found throughout all levels of biosystems, from simple biopolymers,
subcellular organelles, single cells, and macroscopic tissues to bulky organs. Especially …

The accessibility and binding affinity of DNA are two key parameters affecting the
hybridization efficiency in surface-based biosensor technologies. Better accessibility will …

The emergence of multi-drug resistant bacteria is one of the most critical medical problems
currently facing humankind, which will only get worse if no new antibacterial drugs are …

The massive global spread of the COVID-19 pandemic makes the development of more
effective and easily popularized assays critical. Here, we developed an ultrasensitive …

This work presents a comparative study between two functionalization techniques, gold (Au)
and 3-glycidoxypropyl-tri-methoxy silane (GOPTS) that were used to immobilize thiol …

Packaging patterns have close correlation with thermoelastic properties of sensitive layer
and relevant biodetection signals of laminated microbeam. In this paper, we present a cross …

Biofilms formed by pathogenic bacteria present a serious threat to human health as the
efficacy of standard antibiotic therapeutic regimens is compromised by reduced microbial …

Aifantis's strain gradient elasticity theories and Zhang's two-variable method are used to
study elastic bending problems of bilayered micro-cantilever beams, containing a gradient …

In nanoscale diagnostic systems, inhomogeneity in near-surface systems and flexibility in
biostructures greatly influence the mechanical/electrical/thermal properties of biosensors …

Microcantilever-DNA biosensors can lose recognition signals under specific hybridization
conditions; this could be termed as a type of invalid detection. Using a multiscale energy …