Phytochemistry, pharmacology, and potential clinical applications of saffron: A review

B **ng, S Li, J Yang, D Lin, Y Feng, J Lu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Saffron, the dried red stigma of the perennial herb Crocus
sativus L.(Iridaceae), is one of the most important and expensive spices in the world. It is …

The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review

S Nanda, K Madan - Heliyon, 2021 - cell.com
Reactive oxygen species (ROS) are produced as a result of various environmental factors
and cellular metabolism reactions creating oxidative stress. The reversible oxidative …

Antiinflammatory, Antioxidant, and Immunomodulatory Effects of Crocus sativus L. and its Main Constituents

MH Boskabady, T Farkhondeh - Phytotherapy Research, 2016 - Wiley Online Library
Crocus sativus L.(C. sativus), commonly known as saffron, is used as a food additive,
preservative, and medicinal herb. Traditionally, it has been used as an alternative treatment …

Immunomodulatory and anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum leaves and its effect on lung pathological changes in an ovalbumin …

N Eftekhar, A Moghimi… - … and alternative medicine, 2019 - Springer
Abstract Background Ocimum species (Lamiaceae) has been traditionally used for treatment
of upper respiratory tract infections, bronchitis, coughs, sore throat, and wound healing. The …

[HTML][HTML] Saffron (Crocus sativus) petal as a new pharmacological target: a review

A Hosseini, BM Razavi… - Iranian journal of basic …, 2018 - ncbi.nlm.nih.gov
Saffron petal is the main by-product of saffron processing which produced at high level but it
is not applied and thrown out. Saffron petal is containing of several compounds such as …

Saffron: A potential drug-supplement for severe acute respiratory syndrome coronavirus (COVID) management

AM Husaini, KN Jan, GA Wani - Heliyon, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2 (COVID-19), came as a
significant health care challenge for humans in 2019–20. Based on recent laboratory and …

[HTML][HTML] Pharmacological effects of Safranal: An updated review

D Esmaealzadeh, AAM Ghalibaf, MS Rad… - Iranian journal of …, 2023 - ncbi.nlm.nih.gov
Safranal (a monoterpene aldehyde) is the major volatile component of saffron which is
responsible for the saffron unique odor. Several studies have shown the pharmacological …

Safranal, an active ingredient of saffron, attenuates cognitive deficits in amyloid β-induced rat model of Alzheimer's disease: underlying mechanisms

T Baluchnejadmojarad, SM Mohamadi-Zarch… - Metabolic brain …, 2019 - Springer
Alzheimer's disease (AD) is the most prevalent neurodegenerative amyloid disorder with
progressive deterioration of cognitive and memory skills. Despite many efforts, no decisive …

[PDF][PDF] The pharmacology of Crocus sativus-A review

AE Al-Snafi - IOSR Journal of Pharmacy, 2016 - researchgate.net
Saffron contained more than 150 volatile and several nonvolatile compounds, approximately
40–50 constituents have already been identified. It contained apocarotinoid glycosides: in …

Safranal prevents rotenone-induced oxidative stress and apoptosis in an in vitro model of Parkinson's disease through regulating Keap1/Nrf2 signaling pathway

PK Pan, LY Qiao, XN Wen - Cellular and Molecular Biology, 2016 - mail.cellmolbiol.org
Safranal, a major constituent of saffron, possesses antioxidant and anti-apoptotic properties
showing considerable neuroprotective effects. However, whether safranal shows therapeutic …