Building muscle: molecular regulation of myogenesis
The genesis of skeletal muscle during embryonic development and postnatal life serves as a
paradigm for stem and progenitor cell maintenance, lineage specification, and terminal …
paradigm for stem and progenitor cell maintenance, lineage specification, and terminal …
Biomaterials based strategies for skeletal muscle tissue engineering: existing technologies and future trends
Skeletal muscles have a robust capacity to regenerate, but under compromised conditions,
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …
[HTML][HTML] Human ES-and iPS-derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice
R Darabi, RW Arpke, S Irion, JT Dimos, M Grskovic… - Cell stem cell, 2012 - cell.com
A major obstacle in the application of cell-based therapies for the treatment of
neuromuscular disorders is obtaining the appropriate number of stem/progenitor cells to …
neuromuscular disorders is obtaining the appropriate number of stem/progenitor cells to …
Highly porous microcarriers for minimally invasive in situ skeletal muscle cell delivery
Microscale cell carriers have recently garnered enormous interest in repairing tissue defects
by avoiding substantial open surgeries using implants for tissue regeneration. In this study …
by avoiding substantial open surgeries using implants for tissue regeneration. In this study …
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy
Mesoangioblasts are stem/progenitor cells derived from a subset of pericytes found in
muscle that express alkaline phosphatase. They have been shown to ameliorate the …
muscle that express alkaline phosphatase. They have been shown to ameliorate the …
Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells
M Shelton, J Metz, J Liu, RL Carpenedo, SP Demers… - Stem cell reports, 2014 - cell.com
Cell therapies treating pathological muscle atrophy or damage requires an adequate
quantity of muscle progenitor cells (MPCs) not currently attainable from adult donors. Here …
quantity of muscle progenitor cells (MPCs) not currently attainable from adult donors. Here …
Molecular and cellular regulation of skeletal myogenesis
G Comai, S Tajbakhsh - Current topics in developmental biology, 2014 - Elsevier
Since the seminal discovery of the cell-fate regulator Myod, studies in skeletal myogenesis
have inspired the search for cell-fate regulators of similar potential in other tissues and …
have inspired the search for cell-fate regulators of similar potential in other tissues and …
Current strategies for the regeneration of skeletal muscle tissue
Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal
muscle and lead to functional impairment and severe disability. Skeletal muscle …
muscle and lead to functional impairment and severe disability. Skeletal muscle …
Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells
Genetic modification is critically enabling for studies addressing specification and
maintenance of cell fate; however, methods for engineering modifications are inefficient. We …
maintenance of cell fate; however, methods for engineering modifications are inefficient. We …
Master regulators of skeletal muscle lineage development and pluripotent stem cells differentiation
J Esteves de Lima, F Relaix - Cell Regeneration, 2021 - Springer
In vertebrates, the skeletal muscles of the body and their associated stem cells originate
from muscle progenitor cells, during development. The specification of the muscles of the …
from muscle progenitor cells, during development. The specification of the muscles of the …